Head-to-head · Cost-Efficiency Index
Welling Health vs Enhance MD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Welling Health
Patients willing to log meals daily in exchange for a lower effective GLP-1 price.
Visit Welling HealthEnhance MD
Shoppers who want to see every price on the ladder before they commit, value dose-flat billing and routine lab monitoring, and don't need a brand-name or oral route.
Visit Enhance MDThe verdict
Welling Health takes it, leading the Cost-Efficiency Index 78 to 75. Welling Health is a clinician-led metabolic telehealth platform charging a flat $190/month for compounded semaglutide and $275/month for compounded tirzepatide, all doses, with no setup or consultation fees. Enhance MD still earns a C — Shoppers who want to see every price on the ladder before they commit, value dose-flat billing and routine lab monitoring, and don't need a brand-name or oral route.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Welling Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Welling Health | Enhance MD |
|---|---|---|
| Cost-Efficiency Index | 78/100 | 75/100 |
| Semaglutide / mo | $190/mo (all doses, promotional rate, compounded) | $212/mo (first month $112) |
| Tirzepatide / mo | $275/mo (all doses, compounded) | $280/mo (first month $180) |
| Semaglutide / yr (modeled) | $2,280 | $2,544 |
| Tirzepatide / yr (modeled) | $3,300 | $3,360 |
| Coverage | All 50 states | Not disclosed |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #40 | #43 |
Welling Health
78/100Where the value is
- Flat, dose-independent base pricing with no setup or consultation fees disclosed
- Licensed in all 50 states
- Named pharmacy tier (LegitScript-certified 503A, USP <797>) even though the specific pharmacy isn't named
The tradeoffs
- The eye-catching ~30%-off streak price is not the standing rate — it requires 30 unbroken consecutive days of in-app meal logging and resets if a day is missed, so $190/$275 is the realistic price for most patients most of the time
- Tirzepatide's $275 base rate is on the higher end of compounded competitors in this batch
Enhance MD
75/100Where the value is
- Fully published, dose-flat tiered pricing — sema $212/mo, tirz $280/mo, microdose $169/mo, sema+tirz combo $322/mo — no quiz or quote wall
- The rate does not climb as your dose is titrated up, unlike per-mg pricing elsewhere in this ranking
- Routine lab work at the 6-month mark plus ongoing provider messaging is bundled into the price, not sold separately
The tradeoffs
- Compounded only — no FDA-approved brand-name route (no Wegovy, Ozempic, Mounjaro or Zepbound)
- No oral or sublingual GLP-1 option (injection only)
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.