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WeighLab

Head-to-head · Cost-Efficiency Index

Vaylen vs Pepti

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Higher scoreGrade B−

Vaylen

Shoppers who want a GLP-1-only clinic with oral and injectable options in all 50 states.

Visit Vaylen
VS
Grade B−

Pepti

Shoppers who want to see the price of every dose step before they start, with no membership fee on top.

Visit Pepti

The verdict

Too close to callGrade B− vs B−

Vaylen and Pepti tie on the Cost-Efficiency Index at 80/100, so neither wins outright on the numbers, so choose on fit. Vaylen: Shoppers who want a GLP-1-only clinic with oral and injectable options in all 50 states. Pepti: Shoppers who want to see the price of every dose step before they start, with no membership fee on top.

Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Vaylen.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

76
81

Price Transparency

86
84

Nationwide Access

86
86

Formulation Options

90
66

Clinical Oversight

84
86

Contract Flexibility

55
67

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecVaylenPepti
Cost-Efficiency Index80/10080/100
Semaglutide / mo$179/moCompounded$99/mo0.25 mg starting dose, compounded; $109–$199 at higher doses
Tirzepatide / mo$239/moCompounded$159/mo2.5 mg starting dose, compounded; $179–$319 at higher doses
Semaglutide / yr (modeled)$2,148$1,28713 charges
Tirzepatide / yr (modeled)$2,868$2,06713 charges
CoverageAll 50 statesAll 50 states
Oral / sublingualYesNo
Brand-name accessYesCompounded only
Rank here#35#38

Vaylen

80/100

Where the value is

  • Pure GLP-1 specialist — not a multi-category telehealth platform
  • All 50 states coverage with licensed clinicians
  • Both compounded and brand-name options (Ozempic, Wegovy, Zepbound)

The tradeoffs

  • Compounded semaglutide at $179/mo is mid-range (not the cheapest)
  • Brand-name options at near-retail pricing ($997-$1,086/mo)
Visit Vaylen

Full Vaylen review →

Pepti

80/100

Where the value is

  • Every dose has its own published price: semaglutide runs $99 to $199 and tirzepatide $159 to $319
  • No membership fee; the medication price includes physician review, dose adjustments and free shipping
  • Names a reviewing physician and a dispensing pharmacy, Olympia Pharmacy

The tradeoffs

  • The price rises as your dose goes up, so the $99 starting figure covers only the first step of semaglutide
  • It bills every 28 days rather than monthly, which adds up to 13 charges a year
Visit Pepti

Full Pepti review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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