Head-to-head · Cost-Efficiency Index
Vaylen vs NP2GO
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Vaylen
Cost-first shoppers who want gLP-1-focused care with oral and injectable options across all 50 states.
Visit VaylenNP2GO
Shoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves.
Visit NP2GOThe verdict
Vaylen takes it, leading the Cost-Efficiency Index 80 to 79. Vaylen is a pure GLP-1 specialist offering compounded semaglutide ($179/mo), compounded tirzepatide ($239/mo), compounded oral GLP-1 ($259/mo), and brand-name Ozempic, Zepbound, and Wegovy. NP2GO still earns a C — Shoppers inside its 40 served states who want both molecules disclosed and will vet the pharmacy themselves.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Vaylen.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Vaylen | NP2GO |
|---|---|---|
| Cost-Efficiency Index | 80/100 | 79/100 |
| Semaglutide / mo | $179/mo (compounded) | $150/mo |
| Tirzepatide / mo | $239/mo (compounded) | $250/mo |
| Semaglutide / yr (modeled) | $2,148 | $1,800 |
| Tirzepatide / yr (modeled) | $2,868 | $3,000 |
| Coverage | All 50 states | AK, AZ, AR, CA, CO, CT, DE, DC, FL, HI, ID, IL, IA, KS, KY, ME, MD, MA, MI, MN, MT, NE, NV, NH, NJ, NM, NY, ND, OK, OR, PA, RI, SD, TX, UT, VT, VA, WA, WV, WY |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #32 | #33 |
Vaylen
80/100Where the value is
- Pure GLP-1 specialist — not a multi-category telehealth platform
- All 50 states coverage with licensed clinicians
- Both compounded and brand-name options (Ozempic, Wegovy, Zepbound)
The tradeoffs
- Compounded semaglutide at $179/mo is mid-range (not the cheapest)
- Brand-name options at near-retail pricing ($997-$1,086/mo)
NP2GO
79/100Where the value is
- Both molecules disclosed — $150 semaglutide / $250 tirzepatide — for straightforward cost modeling
- Broad 40-state footprint — wider than most non-nationwide operators
- Flat, predictable pricing
The tradeoffs
- 40 states, not all 50 — a coverage gamble that dents its access score
- Not LegitScript-certified — oversight harder to verify
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.