Head-to-head · Cost-Efficiency Index
Vaylen vs Mondae
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Vaylen
Cost-first shoppers who want gLP-1-focused care with oral and injectable options across all 50 states.
Visit VaylenMondae
Cost-first shoppers who want a low all-in price with no membership attached and will count 13 billing cycles a year.
Visit MondaeThe verdict
Vaylen takes it, leading the Cost-Efficiency Index 80 to 79. Vaylen is a pure GLP-1 specialist offering compounded semaglutide ($179/mo), compounded tirzepatide ($239/mo), compounded oral GLP-1 ($259/mo), and brand-name Ozempic, Zepbound, and Wegovy. Mondae still earns a C — Cost-first shoppers who want a low all-in price with no membership attached and will count 13 billing cycles a year.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Vaylen.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Vaylen | Mondae |
|---|---|---|
| Cost-Efficiency Index | 80/100 | 79/100 |
| Semaglutide / mo | $179/mo (compounded) | $87 every 28 days month-to-month (13 charges a year; the advertised $75 is the three-month prepay) |
| Tirzepatide / mo | $239/mo (compounded) | $126 every 28 days month-to-month (the advertised $124 is the three-month prepay) |
| Semaglutide / yr (modeled) | $2,148 | $1,044 |
| Tirzepatide / yr (modeled) | $2,868 | $1,512 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Compounded only |
| Rank here | #32 | #35 |
Vaylen
80/100Where the value is
- Pure GLP-1 specialist — not a multi-category telehealth platform
- All 50 states coverage with licensed clinicians
- Both compounded and brand-name options (Ozempic, Wegovy, Zepbound)
The tradeoffs
- Compounded semaglutide at $179/mo is mid-range (not the cheapest)
- Brand-name options at near-retail pricing ($997-$1,086/mo)
Mondae
79/100Where the value is
- A low all-in figure on both molecules, with the medication, the injection supplies, unlimited clinician messaging and discreet shipping all inside it
- No membership fee and no consultation fee are charged on top of the medication price
- The three-month rate for each molecule is shown by a control on the same page, so the commitment and the monthly rate can be compared directly
The tradeoffs
- "From $75/mo" and "From $124/mo" on the homepage are the three-month prepay rates; the month-to-month rates are $87 and $126
- Billing is every 28 days rather than monthly, so a year costs 13 charges rather than 12
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.