Head-to-head · Cost-Efficiency Index
Tryozi vs Wholesome Clinic
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Tryozi
Shoppers comparing standing rates rather than first-month promo banners.
Visit TryoziWholesome Clinic
Patients in TX/CO/NM/OK/LA/AR/OR who want GLP-1 weight loss bundled with psychiatric/whole-person care from one provider, and who value transparent dose-tiered pricing.
Visit Wholesome ClinicThe verdict
Tryozi and Wholesome Clinic tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers. For most shoppers we'd start with Tryozi (ranked #121, a hair above #123) — Shoppers comparing standing rates rather than first-month promo banners. But Wholesome Clinic is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Tryozi.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Tryozi | Wholesome Clinic |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $279/mo (first-month rate, compounded) | $149/mo (0.5 mg dose, compounded) |
| Tirzepatide / mo | $379/mo (first-month rate, compounded) | $349/mo (5.0 mg dose, compounded) |
| Semaglutide / yr (modeled) | $3,348 | $1,788 |
| Tirzepatide / yr (modeled) | $4,548 | $4,188 |
| Coverage | All 50 states | 7 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Compounded only |
| Rank here | #121 | #123 |
Tryozi
68/100Where the value is
- The site voluntarily discloses its own standing rate ('normally $279/mo') right beside the promo price, which is more transparent than providers that hide it until checkout
- Base labs, consult, medication, and shipping stated as bundled with no hidden fees
- Four named 503A compounding pharmacies rather than one anonymous partner
The tradeoffs
- The prominent $139/$189 banner price is a one-time 50%-off first month only — the real ongoing cost is exactly double, $279/$379/month
- No named individual prescriber or medical director found on the site
Wholesome Clinic
68/100Where the value is
- Real, named, dual-certified prescriber (Stephanie Ukoha, DNP, FNP-BC, PMHNP-BC)
- Transparent dose-tiered pricing for both injectable and oral GLP-1 options, with no evident promo bait-and-switch
- Oral ODT alternatives offer a notably cheaper entry point ($109/mo semaglutide, $249/mo tirzepatide)
The tradeoffs
- Weight loss is a secondary service line to the clinic's core psychiatry focus, not its specialty
- Only licensed in seven states -- far narrower than most national GLP-1 telehealth competitors
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.