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Head-to-head · Cost-Efficiency Index

TrueMe vs Dr. Gillis' Wellness Center

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #152

TrueMe

Cost-first shoppers who want flat all-inclusive GLP-1 pricing, no membership — in its six states.

Visit TrueMe
VS
Grade C · #159

Dr. Gillis' Wellness Center

Cost-first shoppers who want maine-based or Central-Maine patients wanting an experienced, board-certified physician offering sublingual ODT GLP-1 options.

Visit Dr. Gillis' Wellness Center

The verdict

Winner · TrueMeGrade C vs C

TrueMe takes it, leading the Cost-Efficiency Index 66 to 65. TrueMe is a cash-pay telehealth brand offering compounded semaglutide and tirzepatide with added B vitamins, alongside NAD+, sermorelin and glutathione. Dr. Gillis' Wellness Center still earns a CCost-first shoppers who want maine-based or Central-Maine patients wanting an experienced, board-certified physician offering sublingual ODT GLP-1 options.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs TrueMe.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

58
28

Price Transparency

92
78

Nationwide Access

42
86

Formulation Options

79
82

Clinical Oversight

78
89

Contract Flexibility

45
37

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecTrueMeDr. Gillis' Wellness Center
Cost-Efficiency Index66/10065/100
Semaglutide / mo$159/mo (compounded)$250/mo (starting dose, compounded oral)
Tirzepatide / mo$189/mo (compounded)$325/mo (starting dose, compounded)
Semaglutide / yr (modeled)$1,908$3,000
Tirzepatide / yr (modeled)$2,268$3,900
Coverage6 statesAll 50 states
Oral / sublingualNoYes
Brand-name accessYesCompounded only
Rank here#152#159

TrueMe

66/100

Where the value is

  • One price covers consultation, medication, shipping, supplies and provider support, and the site states there are no separate membership fees
  • Same price at every dose, so the cost does not climb as a provider titrates the dose upward
  • Full pricing is published up front — no intake form is required before you can see what you will pay

The tradeoffs

  • Serves only six states (AZ, CO, MO, PA, TX, WI), far narrower coverage than most national GLP-1 telehealth
  • Prices marketed per month are charged every 4 weeks at checkout — 13 charges a year, not 12
Visit TrueMe

Full TrueMe review →

Dr. Gillis' Wellness Center

65/100

Where the value is

  • Led by a board-certified physician/surgeon with 25+ years of experience per the practice's own materials
  • Offers a broad GLP-1 menu — semaglutide, tirzepatide, and retatrutide — in both injectable and needle-free sublingual ODT form
  • No long-term contracts; flexible weekly, bi-weekly, or monthly dosing cadence

The tradeoffs

  • The advertised '$149 starting dose' is just that — a starting dose. The practice's own dedicated pricing page lists semaglutide 'Starting at $250/Month' and tirzepatide 'Starting at $325/month,' both well above the promotional figure
  • Nationwide/all-50-states coverage could not be confirmed on the practice's own site; third-party directories describe it as a Central Maine practice
Visit Dr. Gillis' Wellness Center

Full Dr. Gillis' Wellness Center review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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