Head-to-head · Cost-Efficiency Index
Tru2u vs LumiMeds
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Tru2u
Shoppers comparing a listed catalog price who understand fulfillment happens through a separate, unnamed telehealth partner.
Visit Tru2uLumiMeds
Shoppers willing to prepay a longer term to chase the lowest advertised rate, and who value a named, board-certified medical director.
Visit LumiMedsThe verdict
Tru2u takes it, leading the Cost-Efficiency Index 61 to 60. Tru2u is a DTC wellness storefront (Functional Brands Inc.) listing compounded semaglutide ($225), tirzepatide ($345), and a proprietary combined 'GLP Squared' injection ($275) alongside hair, skincare, and supplement lines. LumiMeds still earns a C — Shoppers willing to prepay a longer term to chase the lowest advertised rate, and who value a named, board-certified medical director.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Tru2u.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Tru2u | LumiMeds |
|---|---|---|
| Cost-Efficiency Index | 61/100 | 60/100 |
| Semaglutide / mo | $225/mo (compounded) | $99/mo (starting dose, 12-month plan, compounded) |
| Tirzepatide / mo | $345/mo (compounded) | $183/mo (starting dose, prepay plan, compounded) |
| Semaglutide / yr (modeled) | $2,700 | $1,188 |
| Tirzepatide / yr (modeled) | $4,140 | $2,196 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #238 | #243 |
Tru2u
61/100Where the value is
- Offers a proprietary combined semaglutide+tirzepatide injection (GLP Squared, $275) not found at most competitors, priced below standalone tirzepatide
- Both injectable and oral-tablet forms listed for semaglutide and tirzepatide at matching prices
- Transparent upfront catalog pricing with free shipping stated on product pages
The tradeoffs
- The product catalog itself is gated behind an 'Apply to Purchase' flow restricted to 'qualified healthcare professionals and practitioners' — it is unclear a typical consumer can buy directly through this listing at all
- No compounding pharmacy is named anywhere, and no LegitScript badge appears on any page checked
LumiMeds
60/100Where the value is
- Named, credentialed Medical Director (Dr. Teresa Walsh, M.D., board certified in obesity medicine, licensed in all 50 states) rather than an anonymous 'board-certified physicians' claim
- LegitScript Certified and HIPAA compliant
- No membership requirement or subscription fee stated separately from the medication price
The tradeoffs
- Both headline prices are explicitly 'as low as' figures across monthly/3/6/12-month options, and the site does not publish what the plain month-to-month rate is versus the prepay-discounted floor — the true standalone monthly cost could not be confirmed
- Compounded medications are, by the site's own disclosure, 'not FDA-approved and have not been evaluated for safety and effectiveness by the FDA'
Regulatory note: the FDA issued a warning letter to Lumimeds in September 2025. We still list and link to LumiMeds; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.