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WeighLab

TrimRx vs Next Vial

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

TrimRx

Provider comparison

Shoppers who want one monthly package that covers the visit, the medication and shipping, and who will confirm the renewal price at checkout.

Semaglutide / month
$299/moMonth-to-month refill price; first month $199, compounded
Tirzepatide / month
$399/moMonth-to-month refill price; first month $349, compounded
Index 77/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check TrimRx pricing Read review

Next Vial

Provider comparison

Shoppers who want a named pharmacy partner and verified LegitScript status without a membership fee.

Semaglutide / month
$199/moMonth-to-month, all doses, compounded
Tirzepatide / month
$249/moMonth-to-month, all doses, compounded
Index 76/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Next Vial pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

TrimRx has the higher Cost-Efficiency Index: 77/100 versus 76/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

TrimRx
All 50 states
Next Vial
49 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

TrimRx

Next Vial

Semaglutide / month
TrimRx: $299/moMonth-to-month refill price; first month $199, compounded
Next Vial: $199/moMonth-to-month, all doses, compounded
Tirzepatide / month
TrimRx: $399/moMonth-to-month refill price; first month $349, compounded
Next Vial: $249/moMonth-to-month, all doses, compounded
Semaglutide / year (modeled)
TrimRx: $3,588
Next Vial: $2,388
Tirzepatide / year (modeled)
TrimRx: $4,788
Next Vial: $2,988
State availability
TrimRx: All 50 states
Next Vial: 49 states
Oral / sublingual option listed
TrimRx: Not listed
Next Vial: Not listed
Brand-name access listed
TrimRx: Yes
Next Vial: Not confirmed
Provider facts checked
TrimRx: October 2026
Next Vial: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

TrimRx

Shoppers who want one monthly package that covers the visit, the medication and shipping, and who will confirm the renewal price at checkout.

Reasons to consider it

  • Each monthly package includes the telehealth consultation, the prescription, the medication and shipping, with no separate membership fee listed
  • The homepage promises the price stays the same as your dose goes up, and offers to keep your current dose if you switch from another program
  • Serves all 50 states, and the terms say so plainly

What to weigh up

  • The homepage says "Starting at $179" and "$259", but the terms list $199 and $349 for the first month and $299 and $399 for each follow-up month, so confirm which price applies to you before paying
  • Once your prescription is sent to the pharmacy that month's order can't be refunded; refunds on prepaid multi-month plans must be requested within 28 days of payment
  • The terms list Ozempic at $1,299 and Zepbound at $1,399 a month, while the site's footer says TrimRx doesn't sell or ship brand-name drugs, so ask how a brand prescription would be filled

Compounded drugs are not FDA-approved. Understand the medication options.

Check TrimRx pricing Read the full TrimRx review

Next Vial

Shoppers who want a named pharmacy partner and verified LegitScript status without a membership fee.

Reasons to consider it

  • Names Manifest Pharmacy as a dispensing partner
  • Displays a LegitScript verification link
  • Publishes a 49-state coverage list, excluding Alaska

What to weigh up

  • The lowest advertised monthly equivalents require paying for a longer supply up front
  • The page headline differs from the actual plan selector, so use the selected plan total
  • No individual medical director is named

Compounded drugs are not FDA-approved. Understand the medication options.

Check Next Vial pricing Read the full Next Vial review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

TrimRxNext Vial
Normalized Cost/Month
TrimRx:
56/100
Next Vial:
68/100
Price Transparency
TrimRx:
94/100
Next Vial:
97/100
Nationwide Access
TrimRx:
86/100
Next Vial:
78/100
Formulation Options
TrimRx:
79/100
Next Vial:
66/100
Clinical Oversight
TrimRx:
85/100
Next Vial:
82/100
Contract Flexibility
TrimRx:
67/100
Next Vial:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

Keep comparing

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.