Head-to-head · Cost-Efficiency Index
Trimi Health vs Vaylen
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Trimi Health
Shoppers who can pay a full year up front, where the annual rate is genuinely among the cheapest all-50 tickets — and who will otherwise budget for the month-to-month rate.
Visit Trimi HealthVaylen
Cost-first shoppers who want gLP-1-focused care with oral and injectable options across all 50 states.
Visit VaylenThe verdict
Vaylen takes it, leading the Cost-Efficiency Index 80 to 78. Vaylen is a pure GLP-1 specialist offering compounded semaglutide ($179/mo), compounded tirzepatide ($239/mo), compounded oral GLP-1 ($259/mo), and brand-name Ozempic, Zepbound, and Wegovy. Trimi Health still earns a C — Shoppers who can pay a full year up front, where the annual rate is genuinely among the cheapest all-50 tickets — and who will otherwise budget for the month-to-month rate.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Vaylen.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Trimi Health | Vaylen |
|---|---|---|
| Cost-Efficiency Index | 78/100 | 80/100 |
| Semaglutide / mo | $175/mo month-to-month ($99/mo only on a 12-month prepay) | $179/mo (compounded) |
| Tirzepatide / mo | $235/mo month-to-month ($125/mo only on a 12-month prepay) | $239/mo (compounded) |
| Semaglutide / yr (modeled) | $2,100 | $2,148 |
| Tirzepatide / yr (modeled) | $2,820 | $2,868 |
| Coverage | All 50 states | All 50 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Yes |
| Rank here | #32 | #34 |
Trimi Health
78/100Where the value is
- Publishes every term rung openly — annual, six-month, quarterly and monthly are all priced on the page rather than revealed at checkout
- Price is flat at every dose, so titrating up does not raise the bill
- Both molecules available on one account, nationwide, with no enrollment or consultation fee
The tradeoffs
- The advertised $99 and $125 rates require a full year paid up front; month-to-month costs $175 and $235, a 77% and 88% premium
- No public LegitScript certification, so pharmacy oversight is harder to independently verify
Vaylen
80/100Where the value is
- Pure GLP-1 specialist — not a multi-category telehealth platform
- All 50 states coverage with licensed clinicians
- Both compounded and brand-name options (Ozempic, Wegovy, Zepbound)
The tradeoffs
- Compounded semaglutide at $179/mo is mid-range (not the cheapest)
- Brand-name options at near-retail pricing ($997-$1,086/mo)
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.