Head-to-head · Cost-Efficiency Index
Trellis Vitality vs Totara Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Trellis Vitality
Shoppers who want a low month-to-month GLP-1 price that holds at every dose, with no membership or consultation fee.
Visit Trellis VitalityTotara Health
Shoppers who want a flat month-to-month GLP-1 price that doesn't climb with the dose, and the option of a tablet or drops instead of a shot.
Visit Totara HealthThe verdict
Trellis Vitality takes it, leading the Cost-Efficiency Index 82 to 80. Trellis Vitality charges $150 a month for compounded semaglutide and $199 for tirzepatide at every dose, with a published table showing small discounts on three- and six-month plans. Totara Health still earns a B− — Shoppers who want a flat month-to-month GLP-1 price that doesn't climb with the dose, and the option of a tablet or drops instead of a shot.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Trellis Vitality.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Trellis Vitality | Totara Health |
|---|---|---|
| Cost-Efficiency Index | 82/100 | 80/100 |
| Semaglutide / mo | $150/moCompounded, month to month; same price at every dose | $190/mo1-month plan, same price at every dose, compounded |
| Tirzepatide / mo | $199/moCompounded, month to month; same price at every dose | $239/mo1-month plan, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $1,800 | $2,280 |
| Tirzepatide / yr (modeled) | $2,388 | $2,868 |
| Coverage | All 50 states | 48 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #29 | #36 |
Trellis Vitality
82/100Where the value is
- A single table shows one-, three- and six-month prices for both drugs, labeled as per-month prices: semaglutide $150, $140 and $133; tirzepatide $199, $189 and $179
- Same price at every dose, so your cost doesn't rise as you titrate up
- No membership fee, no consultation fee, and you can pause or cancel any time
The tradeoffs
- Its NAD+, glutathione, lipo-MIC and tesamorelin programs show only "starting at" prices with no plan table
- The refund policy says only that refunds are decided order by order
Totara Health
80/100Where the value is
- One-month plans are priced on the product page before any intake: $190 for semaglutide and $239 for tirzepatide, the same at every dose
- Semaglutide comes as an injection, oral drops or an under-the-tongue tablet; tirzepatide as an injection or under-the-tongue tablet
- Names its dispensing pharmacy (Manifest Pharmacy in Greer, South Carolina) and its clinician network (MD Integrations)
The tradeoffs
- The lower monthly figures ($133, $119 and $99 for semaglutide) require a 3-, 6- or 12-month plan paid in one charge up front
- The banner says all 50 states, but the FAQ's state list leaves out Alaska and Mississippi
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.