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Head-to-head · Cost-Efficiency Index

Transparent Meds vs Tuyo Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #293

Transparent Meds

Cost-first shoppers who want transparent, upfront monthly pricing on compounded GLP-1 injections.

Visit Transparent Meds
VS
Grade C · #298

Tuyo Health

Shoppers who want a low advertised floor price and are willing to confirm the actual dose-tier cost before committing.

Visit Tuyo Health

The verdict

Winner · Transparent MedsGrade C vs C

Transparent Meds takes it, leading the Cost-Efficiency Index 58 to 57. Transparent Meds is an online GLP-1 weight-care service that connects you with licensed medical providers and leads with upfront pricing: compounded weekly injections of semaglutide at an intro $149/month. Tuyo Health still earns a CShoppers who want a low advertised floor price and are willing to confirm the actual dose-tier cost before committing.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Transparent Meds.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

50
57

Price Transparency

78
78

Nationwide Access

24
24

Formulation Options

79
79

Clinical Oversight

79
64

Contract Flexibility

41
33

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecTransparent MedsTuyo Health
Cost-Efficiency Index58/10057/100
Semaglutide / mo$229/mo (promotional rate, compounded)$155/mo (starting dose, compounded)
Tirzepatide / mo$349/mo (compounded)$279/mo (starting dose, compounded)
Semaglutide / yr (modeled)$2,748$1,860
Tirzepatide / yr (modeled)$4,188$3,348
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoNo
Brand-name accessYesYes
Rank here#293#298

Transparent Meds

58/100

Where the value is

  • Transparent, upfront monthly pricing — intro $149/mo for compounded semaglutide and $249/mo for tirzepatide (regular $229 / $349)
  • Clean, modern telehealth experience with a quick eligibility quiz and clinician review before any prescription
  • HIPAA-compliant and displays a LegitScript-style verification seal

The tradeoffs

  • Headline prices are intro first-month fees — the regular monthly cost is higher ($229 semaglutide, $349 tirzepatide)
  • Connector model that pairs you with licensed providers; it doesn't name its compounding pharmacy
Visit Transparent Meds

Full Transparent Meds review →

Tuyo Health

57/100

Where the value is

  • Quarterly lab work is explicitly bundled into the compounded-track price, unlike sites that omit lab monitoring entirely
  • Offers both compounded and branded (insurance-eligible) tracks on the same platform
  • LegitScript certified

The tradeoffs

  • Both headline prices are explicit 'as low as' floors with no dose-tier table published — the real cost for a titrated-up dose is unknown from the site
  • No compounding pharmacy or individual prescriber/medical director named anywhere on the page
Visit Tuyo Health

Full Tuyo Health review →

Regulatory note: the FDA issued a warning letter to Tuyo Health, Inc. dba Tuyo Health in September 2025. We still list and link to Tuyo Health; you should know the letter is on the public record before you decide.

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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