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Head-to-head · Cost-Efficiency Index

Oxford's Medical Weight Loss (The Calibrate Clinic) vs YourHealthRx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #258

Oxford's Medical Weight Loss (The Calibrate Clinic)

Cost-first shoppers who want a flat, no-contract monthly rate without hunting for hidden membership fees.

Visit Oxford's Medical Weight Loss (The Calibrate Clinic)
VS
Grade C · #260

YourHealthRx

Cost-first shoppers who want science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up.

Visit YourHealthRx

The verdict

Too close to callGrade C vs C

Oxford's Medical Weight Loss (The Calibrate Clinic) and YourHealthRx tie on the Cost-Efficiency Index at 60/100, so neither wins outright on the numbers. For most shoppers we'd start with Oxford's Medical Weight Loss (The Calibrate Clinic) (ranked #258, a hair above #260) — Cost-first shoppers who want a flat, no-contract monthly rate without hunting for hidden membership fees. But YourHealthRx is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Oxford's Medical Weight Loss (The Calibrate Clinic).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

49
53

Price Transparency

78
30

Nationwide Access

42
86

Formulation Options

66
77

Clinical Oversight

72
88

Contract Flexibility

55
33

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecOxford's Medical Weight Loss (The Calibrate Clinic)YourHealthRx
Cost-Efficiency Index60/10060/100
Semaglutide / mo$145/mo (plus a separate fee, compounded)$170/mo (compounded)
Tirzepatide / mo$199/mo (compounded)$210/mo (compounded)
Semaglutide / yr (modeled)$1,740$2,040
Tirzepatide / yr (modeled)$2,388$2,520
Coverage2 statesAll 50 states
Oral / sublingualNoYes
Brand-name accessCompounded onlyCompounded only
Rank here#258#260

Oxford's Medical Weight Loss (The Calibrate Clinic)

60/100

Where the value is

  • Advertised $145/mo GLP-1 rate is genuinely 'all-inclusive' — no separate membership or platform fee stacked on top, unlike the $99-149/mo extra the site's own comparison table says competitors charge
  • No contracts and no cancellation fees stated anywhere in the pricing copy
  • Financing available through CareCredit, Klarna, and Afterpay for patients who want to spread cost

The tradeoffs

  • Site names no medical director, no prescribing physicians, and no compounding pharmacy anywhere — a bigger transparency gap than most peers in this batch
  • No LegitScript seal or third-party pharmacy certification visible on the site
Visit Oxford's Medical Weight Loss (The Calibrate Clinic)

Full Oxford's Medical Weight Loss (The Calibrate Clinic) review →

YourHealthRx

60/100

Where the value is

  • Available in all 50 states and DC through a multi-state (IMLC) licensed clinician network
  • Compounded semaglutide and tirzepatide in two formats - weekly injectable (with B12) or daily oral dissolving tablet
  • Flat subscription price that doesn't change as your dose increases (no titration penalty)

The tradeoffs

  • Eligibility and prescribing run through partner clinical workflows - YourHealthRx is the platform, not the prescriber or pharmacy
  • Compounded medications are not FDA-approved - not brand Wegovy, Ozempic, Zepbound, or Mounjaro
Visit YourHealthRx

Full YourHealthRx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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