Head-to-head · Cost-Efficiency Index
TeleWellnessMD vs Willow
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
TeleWellnessMD
Cost-first shoppers who want not recommended based on headline pricing alone -- always price out the Month 4-5+ maintenance dose before comparing.
Visit TeleWellnessMDWillow
Cost-first shoppers who want an oral-tablet GLP-1 option at the same price as the injectable, with no annual commitment.
Visit WillowThe verdict
TeleWellnessMD and Willow tie on the Cost-Efficiency Index at 49/100, so neither wins outright on the numbers. For most shoppers we'd start with TeleWellnessMD (ranked #426, a hair above #429) — Cost-first shoppers who want not recommended based on headline pricing alone -- always price out the Month 4-5+ maintenance dose before comparing. But Willow is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs TeleWellnessMD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | TeleWellnessMD | Willow |
|---|---|---|
| Cost-Efficiency Index | 49/100 | 49/100 |
| Semaglutide / mo | $349/mo (0.25 mg dose, compounded) | Not disclosed |
| Tirzepatide / mo | $679/mo (2.5 mg dose, compounded) | Not disclosed |
| Semaglutide / yr (modeled) | $4,188 | — |
| Tirzepatide / yr (modeled) | $8,148 | — |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #426 | #429 |
TeleWellnessMD
49/100Where the value is
- Broad GLP-1/GIP product catalog with add-on B-vitamin combination options
- Nationwide state-selector covers all 50 states plus Puerto Rico (with unspecified exceptions)
- Transparent month-by-month price table is at least published in full, not hidden behind a quote wall
The tradeoffs
- Headline prices ($199.95 / $279.95) are lowest-starter-dose only, not the real maintenance cost
- Maintenance-dose pricing is 75-140% higher than the advertised entry price
Willow
49/100Where the value is
- Oral tablet formulations of both semaglutide and tirzepatide, priced identically to the injectable versions ($299/mo and $399/mo respectively) — a genuine format choice most compounded-drug competitors don't offer
- Month-to-month billing with no prepay or annual term required to get the advertised rate
- Named physician team publicly listed, including Chief Medical Officer Dr. Michael Green, MD, plus 11+ other credentialed MDs/DOs
The tradeoffs
- Only 34 states served — notably narrower than WeightlessRx's 49-state footprint; residents of the other 16 states plus DC are excluded
- Site states medication cost 'varies by dosage and prescription' but never discloses what a higher maintenance dose actually costs beyond the $299/$399 starting figures
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.