Head-to-head · Cost-Efficiency Index
SurpassMD vs Sipra
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
SurpassMD
Shoppers who want a published price table by plan length and a price that stays put as the dose goes up.
Visit SurpassMDSipra
Shoppers ready to commit to at least three months who want a price that doesn't rise with the dose and a full price table before they start.
Visit SipraThe verdict
SurpassMD and Sipra tie on the Cost-Efficiency Index at 78/100, so neither wins outright on the numbers, so choose on fit. SurpassMD: Shoppers who want a published price table by plan length and a price that stays put as the dose goes up. Sipra: Shoppers ready to commit to at least three months who want a price that doesn't rise with the dose and a full price table before they start.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs SurpassMD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | SurpassMD | Sipra |
|---|---|---|
| Cost-Efficiency Index | 78/100 | 78/100 |
| Semaglutide / mo | $219/moCompounded, month to month; $175 introductory first month, same price at every dose | $189/mo3-month plan, $567 charged up front, same price at every dose, compounded |
| Tirzepatide / mo | $309/moCompounded, month to month; $247 introductory first month, same price at every dose | $249/mo3-month plan, $747 charged up front, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $2,628 | $2,268 |
| Tirzepatide / yr (modeled) | $3,708 | $2,988 |
| Coverage | All 50 states and D.C. | All 50 states |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #50 | #52 |
SurpassMD
78/100Where the value is
- Each medication page has a full table of 1-, 3-, 6- and 12-month prices, showing both the introductory rate and the standard renewal rate
- One price covers the provider review, medication, shipping and ongoing support, with no separate membership fee
- The price does not rise when your provider increases your dose
The tradeoffs
- The homepage's "as low as $114" and "$177" are introductory prices on a 12-month supply; month to month the standard rates are $219 and $309
- No refunds after cancellation unless you're medically disqualified
Sipra
78/100Where the value is
- A full price table by drug and plan length is published, and the price stays the same as your dose goes up
- Your card isn't charged until a licensed physician reviews and approves your treatment
- Injections, lower-dose microdose injections and dissolving tablets are all offered for both drugs
The tradeoffs
- There's no month-to-month option for GLP-1s: the shortest plan is three months, charged in one payment ($567 for semaglutide, $747 for tirzepatide)
- To stop the next order you have to cancel at least 13 days before your paid period ends
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.