Head-to-head · Cost-Efficiency Index
Sipra vs StaveMD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Sipra
Shoppers ready to commit to at least three months who want a price that doesn't rise with the dose and a full price table before they start.
Visit SipraStaveMD
Shoppers who want an oral or injectable compounded GLP-1 with easy cancellation and are willing to confirm the plan price at checkout.
Visit StaveMDThe verdict
Sipra takes it, leading the Cost-Efficiency Index 78 to 77. Sipra's shortest GLP-1 plan is three months paid up front: $189 a month for compounded semaglutide and $249 for tirzepatide, the same at every dose, with nothing charged until a physician approves. StaveMD still earns a C — Shoppers who want an oral or injectable compounded GLP-1 with easy cancellation and are willing to confirm the plan price at checkout.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Sipra.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Sipra | StaveMD |
|---|---|---|
| Cost-Efficiency Index | 78/100 | 77/100 |
| Semaglutide / mo | $189/mo3-month plan, $567 charged up front, same price at every dose, compounded | $199/moStarting price, compounded injection or dissolving tablet |
| Tirzepatide / mo | $249/mo3-month plan, $747 charged up front, same price at every dose, compounded | $249/moStarting price, compounded |
| Semaglutide / yr (modeled) | $2,268 | $2,388 |
| Tirzepatide / yr (modeled) | $2,988 | $2,988 |
| Coverage | All 50 states | All 50 states and D.C. |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #52 | #57 |
Sipra
78/100Where the value is
- A full price table by drug and plan length is published, and the price stays the same as your dose goes up
- Your card isn't charged until a licensed physician reviews and approves your treatment
- Injections, lower-dose microdose injections and dissolving tablets are all offered for both drugs
The tradeoffs
- There's no month-to-month option for GLP-1s: the shortest plan is three months, charged in one payment ($567 for semaglutide, $747 for tirzepatide)
- To stop the next order you have to cancel at least 13 days before your paid period ends
StaveMD
77/100Where the value is
- Cancel any time from your account with no phone call or notice period, and request a refund for any month whose medication hasn't been ordered
- Offers compounded semaglutide as a weekly injection or a daily dissolving tablet, plus tirzepatide and a lower-dose microdose program from $179 a month
- Names its pharmacies, led by Red Rock Compounding Pharmacy in Utah, and its medical group, OpenLoop Healthcare Partners
The tradeoffs
- Every price is a "starting from" figure; the site says longer programs cost less per month and are billed upfront but doesn't print the price of each plan length
- The banner's "Start for $179/mo" is the microdose program, not the standard semaglutide or tirzepatide dose
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.