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WeighLab

Sipra vs Knownwell

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Sipra

Provider comparison

Shoppers ready to commit to at least three months who want a price that doesn't rise with the dose and a full price table before they start.

Semaglutide / month
$189/mo3-month plan, $567 charged up front, same price at every dose, compounded
Tirzepatide / month
$249/mo3-month plan, $747 charged up front, same price at every dose, compounded
Index 78/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Sipra pricing Read review

Knownwell

Provider comparison

Insured shoppers who want an obesity-medicine specialist overseeing brand-name GLP-1 care, with published self-pay drug prices as a fallback.

Semaglutide / month
$149/moBrand Wegovy pill, 1.5 mg starting dose, visits billed separately; Wegovy pen $349/mo, new patients $199/mo for the first 2 months
Tirzepatide / month
$299/moBrand Zepbound vial or KwikPen, 2.5 mg starting dose, visits billed separately
Index 77/100 · Grade CChecked October 2026
Check Knownwell pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Sipra has the higher Cost-Efficiency Index: 78/100 versus 77/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Sipra

Knownwell

Semaglutide / month
Sipra: $189/mo3-month plan, $567 charged up front, same price at every dose, compounded
Knownwell: $149/moBrand Wegovy pill, 1.5 mg starting dose, visits billed separately; Wegovy pen $349/mo, new patients $199/mo for the first 2 months
Tirzepatide / month
Sipra: $249/mo3-month plan, $747 charged up front, same price at every dose, compounded
Knownwell: $299/moBrand Zepbound vial or KwikPen, 2.5 mg starting dose, visits billed separately
Semaglutide / year (modeled)
Sipra: $2,268
Knownwell: $1,788
Tirzepatide / year (modeled)
Sipra: $2,988
Knownwell: $3,588
State availability
Sipra: All 50 states
Knownwell: All 50 states
Oral / sublingual option listed
Sipra: Yes
Knownwell: Yes
Brand-name access listed
Sipra: Not confirmed
Knownwell: Yes
Provider facts checked
Sipra: October 2026
Knownwell: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Sipra

Shoppers ready to commit to at least three months who want a price that doesn't rise with the dose and a full price table before they start.

Reasons to consider it

  • A full price table by drug and plan length is published, and the price stays the same as your dose goes up
  • Your card isn't charged until a licensed physician reviews and approves your treatment
  • Injections, lower-dose microdose injections and dissolving tablets are all offered for both drugs

What to weigh up

  • There's no month-to-month option for GLP-1s: the shortest plan is three months, charged in one payment ($567 for semaglutide, $747 for tirzepatide)
  • To stop the next order you have to cancel at least 13 days before your paid period ends
  • Leaving a 6- or 12-month plan early is settled under the terms rather than refunded in full

Compounded drugs are not FDA-approved. Understand the medication options.

Check Sipra pricing Read the full Sipra review

Knownwell

Insured shoppers who want an obesity-medicine specialist overseeing brand-name GLP-1 care, with published self-pay drug prices as a fallback.

Reasons to consider it

  • Co-founded and clinically led by Dr. Angela Fitch, a named, credentialed obesity-medicine specialist (Chief Medical Officer)
  • Prescribes branded FDA-approved GLP-1s across the current class (Wegovy, Zepbound, Ozempic, Saxenda) plus orforglipron/Foundayo
  • Publishes a self-pay price for every drug and dose, from $149 a month for the Wegovy pill

What to weigh up

  • Brand-name only, and the price rises with the dose: the Wegovy pill runs $149 to $299 a month, the Wegovy pen $349, and Zepbound $299 to $449
  • Those are medication prices; without insurance, knownwell's own visits cost $299 for the first and $149 for each follow-up
  • In-person care is limited to five states (Texas has primary care in Plano only), so most of the country can only use the virtual clinic
Check Knownwell pricing Read the full Knownwell review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

SipraKnownwell
Normalized Cost/Month
Sipra:
64/100
Knownwell:
73/100
Price Transparency
Sipra:
97/100
Knownwell:
72/100
Nationwide Access
Sipra:
86/100
Knownwell:
86/100
Formulation Options
Sipra:
77/100
Knownwell:
95/100
Clinical Oversight
Sipra:
78/100
Knownwell:
82/100
Contract Flexibility
Sipra:
61/100
Knownwell:
55/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.