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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs Velvet Rx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #3

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade C · #257

Velvet Rx

Cost-first shoppers who want cash-pay compounded GLP-1 with bundled shipping across three SKUs.

Visit Velvet Rx

The verdict

Winner · ShedRx (Shed)Grade B+ vs C

ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 59. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. Velvet Rx still earns a CCost-first shoppers who want cash-pay compounded GLP-1 with bundled shipping across three SKUs.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
51

Price Transparency

74
86

Nationwide Access

92
24

Formulation Options

96
77

Clinical Oversight

84
68

Contract Flexibility

76
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)Velvet Rx
Cost-Efficiency Index87/10059/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$299/mo (compounded)
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$359/mo (compounded)
Semaglutide / yr (modeled)$2,388$3,588
Tirzepatide / yr (modeled)$3,588$4,308
CoverageAll 50 statesCoverage not published
Oral / sublingualYesYes
Brand-name accessYesCompounded only
Rank on the board#3#257

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

Velvet Rx

59/100

Where the value is

  • Public pricing across 3 SKUs (semaglutide $299, tirzepatide $359, oral GLP-1 $349) — uncommon in compounded telehealth
  • First-month promo pricing shown upfront ($139 sema / $199 tirz / $189 oral)
  • Single monthly price includes consult, prescription, 4 weeks of medication, and free 1–2 day shipping

The tradeoffs

  • Oral GLP-1 SKU doesn't name the specific drug — a real gap given Rybelsus, Foundayo, and compounded oral semaglutide differ clinically
  • No LegitScript or NABP .pharmacy seal displayed
Visit Velvet Rx

Full Velvet Rx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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