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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs NuuVim

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #3

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade C · #114

NuuVim

Cost-first shoppers who want low-cost compounded GLP-1s (injection or oral), flat all-dose pricing.

Visit NuuVim

The verdict

Winner · ShedRx (Shed)Grade B+ vs C

ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 69. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. NuuVim still earns a CCost-first shoppers who want low-cost compounded GLP-1s (injection or oral), flat all-dose pricing.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
94

Price Transparency

74
94

Nationwide Access

92
24

Formulation Options

96
90

Clinical Oversight

84
42

Contract Flexibility

76
47

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)NuuVim
Cost-Efficiency Index87/10069/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$79/mo (all doses, 3-mo plan, new patients only, compounded)
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$133/mo (all doses, 3-mo plan, new patients only, compounded)
Semaglutide / yr (modeled)$2,388$948
Tirzepatide / yr (modeled)$3,588$1,596
CoverageAll 50 statesCoverage not published
Oral / sublingualYesYes
Brand-name accessYesYes
Rank on the board#3#114

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

NuuVim

69/100

Where the value is

  • Low compounded entry pricing — semaglutide from $79/mo, tirzepatide from $133/mo, flat all-dose pricing
  • Both injectable and oral compounded options for semaglutide and tirzepatide (oral access is uncommon)
  • LegitScript Certified and HIPAA-compliant

The tradeoffs

  • There is no month-to-month plan: every rate is billed as one three-month payment
  • The advertised $79 and $133 are introductory rates for customers new to GLP-1s; on renewal they become $133 and $199.67
Visit NuuVim

Full NuuVim review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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