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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs Mevo Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #3

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade C · #237

Mevo Health

Cost-first shoppers who want physician-network GLP-1 in injection and oral-tablet forms.

Visit Mevo Health

The verdict

Winner · ShedRx (Shed)Grade B+ vs C

ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 60. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. Mevo Health still earns a CCost-first shoppers who want physician-network GLP-1 in injection and oral-tablet forms.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
62

Price Transparency

74
94

Nationwide Access

92
24

Formulation Options

96
77

Clinical Oversight

84
68

Contract Flexibility

76
20

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)Mevo Health
Cost-Efficiency Index87/10060/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$199/mo (all doses, compounded)
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$259/mo (all doses, compounded)
Semaglutide / yr (modeled)$2,388$2,388
Tirzepatide / yr (modeled)$3,588$3,108
CoverageAll 50 statesCoverage not published
Oral / sublingualYesYes
Brand-name accessYesCompounded only
Rank on the board#3#237

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

Mevo Health

60/100

Where the value is

  • LegitScript verification badge on multiple pages
  • Publishes the FDA compounded-medication disclaimer
  • Four named board-certified physicians disclosed (Wasef, Suppa, Sakla, Chikando)

The tradeoffs

  • States served not listed on any public page
  • Pharmacy partners not named (only '503A U.S. compounding pharmacies' with unlabeled logos)
Visit Mevo Health

Full Mevo Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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