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Head-to-head · Cost-Efficiency Index

ShedRx (Shed) vs KERNX Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #3

ShedRx (Shed)

People who want a needle-free route or a brand-name option, and who will commit to twelve months to reach the lowest price.

Visit ShedRx (Shed)
VS
Grade C · #287

KERNX Health

Shoppers who want plan pricing published up front and month-to-month billing.

Visit KERNX Health

The verdict

Winner · ShedRx (Shed)Grade B+ vs C

ShedRx (Shed) takes it, leading the Cost-Efficiency Index 87 to 56. The widest set of formats on the board — injection, drops, lozenges and a daily oral pill, plus a real brand Zepbound route — though its cheapest advertised rates need a year-long commitment. KERNX Health still earns a CShoppers who want plan pricing published up front and month-to-month billing.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs ShedRx (Shed).

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
59

Price Transparency

74
72

Nationwide Access

92
24

Formulation Options

96
66

Clinical Oversight

84
71

Contract Flexibility

76
45

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecShedRx (Shed)KERNX Health
Cost-Efficiency Index87/10056/100
Semaglutide / mo$199/mo ($159 on a 12-month plan)$129/mo (promotional rate, plus a separate fee, compounded)
Tirzepatide / mo$299/mo ($239 on a 12-month plan)$199/mo (promotional rate, plus a separate fee, compounded)
Semaglutide / yr (modeled)$2,388$1,548
Tirzepatide / yr (modeled)$3,588$2,388
CoverageAll 50 statesCoverage not published
Oral / sublingualYesNo
Brand-name accessYesCompounded only
Rank on the board#3#287

ShedRx (Shed)

87/100

Where the value is

  • Four routes to a GLP-1 — injection, liquid drops, lozenges and a daily oral pill
  • Brand Zepbound and Wegovy available alongside the compounded line
  • Available in all 50 states, with health coaching included and a published 120-day weight-loss guarantee

The tradeoffs

  • The advertised "as low as" prices ($159 semaglutide, $239 tirzepatide) require a TWELVE-MONTH commitment — month-to-month is $199 and $299
  • Compounded medication is not FDA-approved the way brand Ozempic, Wegovy, or Zepbound are
Visit ShedRx (Shed)

Full ShedRx (Shed) review →

KERNX Health

56/100

Where the value is

  • Publishes plan pricing openly, before any intake or account creation
  • Month-to-month with no long-term contract and no multi-month prepayment
  • Billing starts only after a licensed provider approves treatment

The tradeoffs

  • Its own pricing page contradicts itself: it claims no separate consultation charges, then states a $25-$60 fee applies per visit
  • The consultation fee is charged whether or not a prescription is issued
Visit KERNX Health

Full KERNX Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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