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Head-to-head · Cost-Efficiency Index

Sesame Care vs Eden

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B · #6

Sesame Care

People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost.

Visit Sesame Care
VS
Grade B · #7

Eden

People who will trade a higher sticker price for verified nationwide access and stronger clinical oversight.

Visit Eden

The verdict

Too close to callGrade B vs B

Sesame Care and Eden tie on the Cost-Efficiency Index at 86/100, so neither wins outright on the numbers. For most shoppers we'd start with Sesame Care (ranked #6, a hair above #7) — People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost. But Eden is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Sesame Care.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

76
80

Price Transparency

82
90

Nationwide Access

92
96

Formulation Options

95
82

Clinical Oversight

89
92

Contract Flexibility

84
88

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecSesame CareEden
Cost-Efficiency Index86/10086/100
Semaglutide / mo$149/mo (brand)$239/mo
Tirzepatide / moBrand (Zepbound)$349/mo
Semaglutide / yr (modeled)$2,868
Tirzepatide / yr (modeled)$4,188
CoverageNationwideAll 50 states
Oral / sublingualYesNo
Brand-name accessYesCompounded only
Rank on the board#6#7

Sesame Care

86/100

Where the value is

  • Widest brand-name formulary we list — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and oral Rybelsus, all FDA-approved rather than compounded
  • Established national marketplace operating since 2018, with LegitScript certification and BBB recognition
  • Wegovy pill starts around $149/mo, and oral routes are available for the needle-averse

The tradeoffs

  • Two-part cost — the medication price is separate from a platform subscription, so the all-in monthly runs above the $149 headline
  • A generalist telehealth marketplace, not a dedicated GLP-1 program
Visit Sesame Care

Full Sesame Care review →

Eden

86/100

Where the value is

  • High transparency — clear supply-chain and clinician disclosure lowers hidden-cost risk
  • Nationwide availability with both molecules disclosed
  • Strong clinical oversight adds value beyond the raw price

The tradeoffs

  • Premium per-month cost drags its normalized value score
  • Compounded only — no brand-name access
Visit Eden

Full Eden review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

Keep comparing

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