Head-to-head · Cost-Efficiency Index
RxPros vs Medical Health Institute
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
RxPros
Shoppers who want the lowest ongoing per-month compounded rate and don't mind a higher-priced first order.
Visit RxProsMedical Health Institute
Shoppers comparing across TRT, peptides, and weight loss under one provider who don't need public pricing detail up front.
Visit Medical Health InstituteThe verdict
RxPros and Medical Health Institute tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers. For most shoppers we'd start with RxPros (ranked #120, a hair above #125) — Shoppers who want the lowest ongoing per-month compounded rate and don't mind a higher-priced first order. But Medical Health Institute is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs RxPros.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | RxPros | Medical Health Institute |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $100/mo (all doses, compounded) | $100/mo (all doses, compounded) |
| Tirzepatide / mo | $145/mo (all doses, compounded) | Not disclosed |
| Semaglutide / yr (modeled) | $1,200 | $1,200 |
| Tirzepatide / yr (modeled) | $1,740 | — |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #120 | #125 |
RxPros
68/100Where the value is
- Flat recurring price of $99.97/mo (sema) and $144.97/mo (tirz) — no per-mg price increase as you titrate up doses
- No membership fee and no mandatory commitment despite an annual-prepay discount option — 'Cancel Subscription Anytime' stated directly
- Ships a 3-month supply per order rather than monthly reshipments
The tradeoffs
- The advertised $99.97/mo (sema) and $144.97/mo (tirz) rates are NOT what a first-time buyer pays — the actual first order is $149 and $249 respectively, 49-72% higher than the headline
- Specific pharmacy partner is not named — a proprietary system routes among unnamed 503A pharmacies and 'cannot guarantee' which one fills any given order
Medical Health Institute
68/100Where the value is
- Advertises a competitively low $100/mo entry price for GLP-1 weight loss
- Offers multiple service lines (weight loss, TRT, peptide therapy) under one provider
- LegitScript and HIPAA-compliance badges both displayed on the homepage
The tradeoffs
- The $100/mo headline price carries the company's own asterisk — '*Based on pharmacy availability' — meaning it is explicitly not a guaranteed rate before intake
- No dose tier or even which drug (semaglutide vs. tirzepatide) the $100 figure applies to is disclosed anywhere public
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.