Head-to-head · Cost-Efficiency Index
RxION Health vs Magnolia Regenerative Medicine
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
RxION Health
Cost-first shoppers who want a flat, dose-independent monthly price with no titration surcharges, outside NJ/AK/MS.
Visit RxION HealthMagnolia Regenerative Medicine
Readers in one of the 26 states it treats who want a titration plan priced per step and will not need to cancel by email.
Visit Magnolia Regenerative MedicineThe verdict
RxION Health and Magnolia Regenerative Medicine tie on the Cost-Efficiency Index at 57/100, so neither wins outright on the numbers. For most shoppers we'd start with RxION Health (ranked #300, a hair above #307) — Cost-first shoppers who want a flat, dose-independent monthly price with no titration surcharges, outside NJ/AK/MS. But Magnolia Regenerative Medicine is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs RxION Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | RxION Health | Magnolia Regenerative Medicine |
|---|---|---|
| Cost-Efficiency Index | 57/100 | 57/100 |
| Semaglutide / mo | $99/mo (all doses, plus a separate fee, compounded) | $119.00/month month-to-month (the advertised $99 is a three-month prepay at the flat minimum dose) |
| Tirzepatide / mo | $183/mo (all doses, compounded) | $199.00/month month-to-month (the advertised $179 is a three-month prepay at the flat minimum dose) |
| Semaglutide / yr (modeled) | $1,188 | $1,428 |
| Tirzepatide / yr (modeled) | $2,196 | $2,388 |
| Coverage | Coverage not published | 26 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #300 | #307 |
RxION Health
57/100Where the value is
- One flat monthly price regardless of dose — no per-mg price ladder to climb as you titrate up
- Free cold-pack overnight shipping and injection supplies stated as included on both drug pages
- LegitScript Certified badge displayed and independently verifiable
The tradeoffs
- The displayed $99/$183 prices sit against a struck-through $199/$299 'regular' price with no stated end date — it is unclear whether this is a permanent or temporary rate
- Not available to residents of New Jersey, Alaska, or Mississippi
Magnolia Regenerative Medicine
57/100Where the value is
- Publishes an explicit 26-state telehealth list rather than an unverifiable nationwide claim
- Prices a new-patient titration plan separately from a continuing-patient plan, so the cost of stepping up a dose is visible rather than assumed
- Runs two physical clinics and says so, which is unusual for a compounded GLP-1 seller
The tradeoffs
- The advertised "starting at $99" and "starting at $179" are three-month prepay figures; the month-to-month rates are $119 and $199, and the arithmetic behind that is on the site itself
- A first-time patient cannot buy the advertised price at all — answering that this is your first time yields titration plans at $119 and $199 a month
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.