Head-to-head · Cost-Efficiency Index
ReflexMD vs Pillar Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
ReflexMD
Shoppers who want one flat monthly price that won't rise with the dose and who are comfortable canceling by phone.
Visit ReflexMDPillar Health
Shoppers who want one flat monthly price for compounded semaglutide or tirzepatide that won't rise as the dose goes up.
Visit Pillar HealthThe verdict
ReflexMD and Pillar Health tie on the Cost-Efficiency Index at 75/100, so neither wins outright on the numbers, so choose on fit. ReflexMD: Shoppers who want one flat monthly price that won't rise with the dose and who are comfortable canceling by phone. Pillar Health: Shoppers who want one flat monthly price for compounded semaglutide or tirzepatide that won't rise as the dose goes up.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs ReflexMD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | ReflexMD | Pillar Health |
|---|---|---|
| Cost-Efficiency Index | 75/100 | 75/100 |
| Semaglutide / mo | $297/moCompounded, same price at every dose, month to month | $189/moCompounded, same price at every dose; first month $94.50 with the welcome code |
| Tirzepatide / mo | $367/moCompounded, same price at every dose, month to month | $249/moCompounded, same price at every dose; first month $124.50 with the welcome code |
| Semaglutide / yr (modeled) | $3,564 | $2,268 |
| Tirzepatide / yr (modeled) | $4,404 | $2,988 |
| Coverage | All 50 states | 48 states + DC |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #69 | #70 |
ReflexMD
75/100Where the value is
- Both prices are shown on the homepage before any quiz, and the site calls them flat-rate pricing
- The online consultation fee is included in the subscription, and shipping is free and overnight once the pharmacy ships
- Month to month with no long-term contract; 3- and 6-month plans are optional, with 15% off 3-month plans under a current promo code
The tradeoffs
- Outside California you must call to cancel, at least two days before the renewal date; California residents can also cancel by email
- Fees already paid are not refunded once the month is billed
Pillar Health
75/100Where the value is
- Both monthly prices are on the weight-loss and product pages before any questionnaire, with $0 membership and free shipping
- The program price covers every dose in the titration ladder, from 0.25 mg to 2.4 mg of semaglutide and 2.5 mg to 15 mg of tirzepatide
- Publishes where it serves: 48 states and Washington, D.C., with Alaska and Mississippi excluded
The tradeoffs
- Pillar is a storefront: starting treatment hands you to a separate checkout platform whose own terms set the charges, renewals, cancellations and refunds
- Its refund policy points you to that provider's terms rather than stating its own cancellation or refund rules
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.