Head-to-head · Cost-Efficiency Index
Refills vs Roen Rx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Refills
Cost-first shoppers who want a single account across GLP-1, ED, and hair-growth care, for shoppers willing to price-shop through intake before seeing a final number.
Visit RefillsRoen Rx
Cost-first shoppers who want insured shoppers chasing a low brand-name copay via RoenRx's insurance coordination, with a compounded fallback.
Visit Roen RxThe verdict
Refills and Roen Rx tie on the Cost-Efficiency Index at 46/100, so neither wins outright on the numbers. For most shoppers we'd start with Refills (ranked #453, a hair above #454) — Cost-first shoppers who want a single account across GLP-1, ED, and hair-growth care, for shoppers willing to price-shop through intake before seeing a final number. But Roen Rx is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Refills.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Refills | Roen Rx |
|---|---|---|
| Cost-Efficiency Index | 46/100 | 46/100 |
| Semaglutide / mo | Not disclosed | $151/mo (starting dose, 3-month plan, plus a separate fee, compounded) |
| Tirzepatide / mo | Not disclosed | $216/mo (starting dose, plus a separate fee, compounded) |
| Semaglutide / yr (modeled) | — | $1,812 |
| Tirzepatide / yr (modeled) | — | $2,592 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #453 | #454 |
Refills
46/100Where the value is
- LegitScript-certified online pharmacy, badge confirmed on /how-refills-works
- Backed by named clinician network partners (Beluga Health, Bask Health, Wasef Health) rather than an anonymous 'doctor network'
- Multi-category platform (weight loss + ED + hair growth) under one account
The tradeoffs
- The only public price signal is the marketing headline 'GLP-1s from $5/Day' (~$150/mo) — there is no per-drug, per-dose, or itemized monthly breakdown anywhere on the site; real cost only appears deep in the my.refills.com intake funnel
- Neither the compounding pharmacy nor a medical director is named anywhere on the public site
Regulatory note: the FDA issued a warning letter to Refills Health, LLC dba Refills Health in February 2026. We still list and link to Refills; you should know the letter is on the public record before you decide.
Roen Rx
46/100Where the value is
- Insurance coordination path can bring brand-name GLP-1s down to as low as $25/mo for covered patients
- Both compounded and brand-name (Ozempic, Wegovy, Zepbound, Mounjaro) options on one platform
- Explicitly serves all 50 states and DC
The tradeoffs
- The advertised LegitScript badge on the homepage is literally commented out in the page's HTML source and never renders on the live site — despite being present in source, it is not a real, visible certification a visitor sees
- Medication cost and membership fee are billed separately; the membership's regular (non-promotional) monthly price is never disclosed anywhere checked, only the '$39 first month' discount
Regulatory note: the FDA issued a warning letter to Roen Health, Inc. dba RoenRx in June 2026. We still list and link to Roen Rx; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.