Head-to-head · Cost-Efficiency Index
PreventiveMD vs TrimRx
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
PreventiveMD
Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths.
Visit PreventiveMDTrimRx
Shoppers who want one monthly package that covers the visit, the medication and shipping, and who will confirm the renewal price at checkout.
Visit TrimRxThe verdict
PreventiveMD and TrimRx tie on the Cost-Efficiency Index at 77/100, so neither wins outright on the numbers, so choose on fit. PreventiveMD: Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths. TrimRx: Shoppers who want one monthly package that covers the visit, the medication and shipping, and who will confirm the renewal price at checkout.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs PreventiveMD.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | PreventiveMD | TrimRx |
|---|---|---|
| Cost-Efficiency Index | 77/100 | 77/100 |
| Semaglutide / mo | $83/moAs low as, term not published, all-in, compounded | $299/moMonth-to-month refill price; first month $199, compounded |
| Tirzepatide / mo | $97/moAs low as, term not published, all-in, compounded | $399/moMonth-to-month refill price; first month $349, compounded |
| Semaglutide / yr (modeled) | $996 | $3,588 |
| Tirzepatide / yr (modeled) | $1,164 | $4,788 |
| Coverage | 36 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Yes | Yes |
| Rank here | #53 | #56 |
PreventiveMD
77/100Where the value is
- Compounded semaglutide from $83/mo and tirzepatide from $97/mo, billed as one all-in monthly price
- Brand Wegovy, Zepbound, and Foundayo (oral GLP-1) available on the same platform
- US-licensed provider reviews requests within 24 hours — no video visit required
The tradeoffs
- Both figures are 'as low as' rates and the qualifying term is not published anywhere — the checkout is gated, so whether $97 is month-to-month or a multi-month prepay cannot be established before signing up
- Brand-name routes are priced separately and do carry a fee: $49/mo membership plus medication from $149/mo for Foundayo and Wegovy, from $299/mo for Zepbound
TrimRx
77/100Where the value is
- Each monthly package includes the telehealth consultation, the prescription, the medication and shipping, with no separate membership fee listed
- The homepage promises the price stays the same as your dose goes up, and offers to keep your current dose if you switch from another program
- Serves all 50 states, and the terms say so plainly
The tradeoffs
- The homepage says "Starting at $179" and "$259", but the terms list $199 and $349 for the first month and $299 and $399 for each follow-up month, so confirm which price applies to you before paying
- Once your prescription is sent to the pharmacy that month's order can't be refunded; refunds on prepaid multi-month plans must be requested within 28 days of payment
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.