PreventiveMD vs Knownwell

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

PreventiveMD

Provider comparison

Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths.

Semaglutide / month: $83/moAs low as, term not published, all-in, compounded
Tirzepatide / month: $97/moAs low as, term not published, all-in, compounded

Index 77/100 · Grade CChecked August 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check PreventiveMD pricing Read review

Knownwell

Provider comparison

Insured shoppers who want an obesity-medicine specialist overseeing brand-name GLP-1 care, with published self-pay drug prices as a fallback.

Semaglutide / month: $149/moBrand Wegovy pill, 1.5 mg starting dose, visits billed separately; Wegovy pen $349/mo, new patients $199/mo for the first 2 months
Tirzepatide / month: $299/moBrand Zepbound vial or KwikPen, 2.5 mg starting dose, visits billed separately

Index 77/100 · Grade CChecked October 2026

Check Knownwell pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 77/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

PreventiveMD: 36 states
Knownwell: All 50 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

PreventiveMD

Knownwell

Semaglutide / month: PreventiveMD: $83/moAs low as, term not published, all-in, compounded; Knownwell: $149/moBrand Wegovy pill, 1.5 mg starting dose, visits billed separately; Wegovy pen $349/mo, new patients $199/mo for the first 2 months

Tirzepatide / month: PreventiveMD: $97/moAs low as, term not published, all-in, compounded; Knownwell: $299/moBrand Zepbound vial or KwikPen, 2.5 mg starting dose, visits billed separately

Semaglutide / year (modeled): PreventiveMD: $996; Knownwell: $1,788

Tirzepatide / year (modeled): PreventiveMD: $1,164; Knownwell: $3,588

State availability: PreventiveMD: 36 states; Knownwell: All 50 states

Oral / sublingual option listed: PreventiveMD: Not listed; Knownwell: Yes

Brand-name access listed: PreventiveMD: Yes; Knownwell: Yes

Provider facts checked: PreventiveMD: August 2026; Knownwell: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

PreventiveMD

Cost-first shoppers who want compounded GLP-1s from $83/mo all-in, with brand upgrade paths.

Reasons to consider it

Compounded semaglutide from $83/mo and tirzepatide from $97/mo, billed as one all-in monthly price
Brand Wegovy, Zepbound, and Foundayo (oral GLP-1) available on the same platform
US-licensed provider reviews requests within 24 hours — no video visit required

What to weigh up

Both figures are 'as low as' rates and the qualifying term is not published anywhere — the checkout is gated, so whether $97 is month-to-month or a multi-month prepay cannot be established before signing up
Brand-name routes are priced separately and do carry a fee: $49/mo membership plus medication from $149/mo for Foundayo and Wegovy, from $299/mo for Zepbound
No state count is published, and a state-variant waitlist implies some states are unserved

Compounded drugs are not FDA-approved. Understand the medication options.

Check PreventiveMD pricing Read the full PreventiveMD review

Knownwell

Insured shoppers who want an obesity-medicine specialist overseeing brand-name GLP-1 care, with published self-pay drug prices as a fallback.

Reasons to consider it

Co-founded and clinically led by Dr. Angela Fitch, a named, credentialed obesity-medicine specialist (Chief Medical Officer)
Prescribes branded FDA-approved GLP-1s across the current class (Wegovy, Zepbound, Ozempic, Saxenda) plus orforglipron/Foundayo
Publishes a self-pay price for every drug and dose, from $149 a month for the Wegovy pill

What to weigh up

Brand-name only, and the price rises with the dose: the Wegovy pill runs $149 to $299 a month, the Wegovy pen $349, and Zepbound $299 to $449
Those are medication prices; without insurance, knownwell's own visits cost $299 for the first and $149 for each follow-up
In-person care is limited to five states (Texas has primary care in Plano only), so most of the country can only use the virtual clinic

Check Knownwell pricing Read the full Knownwell review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PreventiveMDKnownwell

Normalized Cost/Month: PreventiveMD:
87/100; Knownwell:
73/100

Price Transparency: PreventiveMD:
78/100; Knownwell:
72/100

Nationwide Access: PreventiveMD:
66/100; Knownwell:
86/100

Formulation Options: PreventiveMD:
84/100; Knownwell:
95/100

Clinical Oversight: PreventiveMD:
82/100; Knownwell:
82/100

Contract Flexibility: PreventiveMD:
55/100; Knownwell:
55/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.