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Head-to-head · Cost-Efficiency Index

PrescribedRX vs Avono Health

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #412

PrescribedRX

Shoppers who want flat, dose-independent pricing and are also interested in bundling TRT or hair loss treatment on the same platform.

Visit PrescribedRX
VS
Grade C · #419

Avono Health

Shoppers specifically wanting an oral-capsule semaglutide option and willing to prepay a full quarter.

Visit Avono Health

The verdict

Winner · PrescribedRXGrade C vs C

PrescribedRX takes it, leading the Cost-Efficiency Index 50 to 49. PrescribedRX is a multi-category telehealth platform offering compounded injectable semaglutide and tirzepatide for weight loss alongside TRT, hair loss, and sexual health treatments. Avono Health still earns a CShoppers specifically wanting an oral-capsule semaglutide option and willing to prepay a full quarter.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs PrescribedRX.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

59
21

Price Transparency

46
78

Nationwide Access

24
24

Formulation Options

66
64

Clinical Oversight

80
80

Contract Flexibility

20
47

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecPrescribedRXAvono Health
Cost-Efficiency Index50/10049/100
Semaglutide / mo$189/mo (all doses, prepay plan, compounded)$699/mo (3-month plan, compounded)
Tirzepatide / mo$276/mo (all doses, prepay plan, compounded)Not disclosed
Semaglutide / yr (modeled)$2,268$8,388
Tirzepatide / yr (modeled)$3,312
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessCompounded onlyCompounded only
Rank here#412#419

PrescribedRX

50/100

Where the value is

  • Dose-flat pricing -- cost doesn't increase as you titrate up
  • Both compounded semaglutide and tirzepatide offered
  • LegitScript badge displayed

The tradeoffs

  • 3-month tirzepatide 'starting at' price is a $697 upfront prepay trap, not the real monthly rate
  • Confusing bundle pricing where the 'special offer' is actually pricier than the plain monthly plan
Visit PrescribedRX

Full PrescribedRX review →

Avono Health

49/100

Where the value is

  • Offers a genuinely rare oral-capsule semaglutide format, not just injectable
  • Transparent that pricing is a 3-month bundle rather than hiding the prepay structure
  • US-nationwide clinician network claimed

The tradeoffs

  • 'Saves $X vs. monthly' claims can't be verified since the standalone monthly price is never disclosed
  • No tirzepatide offering at all -- semaglutide only
Visit Avono Health

Full Avono Health review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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