PlushCare vs NuDay Rx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

PlushCare

Provider comparison

Patients who want a real board-certified physician managing GLP-1s alongside general primary care, and are prepared to navigate insurance or a manufacturer cash-pay program rather than a single flat price.

Semaglutide / month: $499/moBrand Wegovy through NovoCare Pharmacy, plus a separate fee
Tirzepatide / month: $299/mo2.5 mg brand Zepbound vial through LillyDirect; $399 at 5 mg, $449 at 7.5 mg and up, plus a separate fee

Index 61/100 · Grade CChecked October 2026

Check PlushCare pricing Read review

NuDay Rx

Provider comparison

Shoppers who want both compounded and brand-name GLP-1 options with a named pharmacy on one platform.

Semaglutide / month: $249/moCompounded
Tirzepatide / month: $329/moCompounded

Index 61/100 · Grade CChecked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check NuDay Rx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Both score 61/100 on the Cost-Efficiency Index. There is no score winner; compare the treatment you need, billing terms and state availability.

Check the difference in state access

PlushCare: All 50 states
NuDay Rx: Coverage not published

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

PlushCare

NuDay Rx

Semaglutide / month: PlushCare: $499/moBrand Wegovy through NovoCare Pharmacy, plus a separate fee; NuDay Rx: $249/moCompounded

Tirzepatide / month: PlushCare: $299/mo2.5 mg brand Zepbound vial through LillyDirect; $399 at 5 mg, $449 at 7.5 mg and up, plus a separate fee; NuDay Rx: $329/moCompounded

Semaglutide / year (modeled): PlushCare: $6,228Includes $19.99/mo membership; NuDay Rx: $2,988

Tirzepatide / year (modeled): PlushCare: $3,828Includes $19.99/mo membership; NuDay Rx: $3,948

State availability: PlushCare: All 50 states; NuDay Rx: Coverage not published

Oral / sublingual option listed: PlushCare: Not listed; NuDay Rx: Yes

Brand-name access listed: PlushCare: Yes; NuDay Rx: Yes

Provider facts checked: PlushCare: October 2026; NuDay Rx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

PlushCare

Reasons to consider it

Board-certified physicians (not NP-only) available in all 50 states for general virtual primary care
Lists the Zepbound self-pay prices by dose on its own page: vials at $299, $399 and $449 a month, pens at $650
Owned by Transcarent, a venture-backed platform with a named, traceable corporate lineage

What to weigh up

Compounded semaglutide ($149 at 0.25 mg, $299 above) is offered only while the brand drug is on FDA's shortage list, and compounded options only in 40 states plus DC
A $19.99/mo membership (first month free) and, without insurance, a $129 visit come on top of the medication price
The Wegovy page still quotes a $199 first-months price 'valid through March 2026', a date that has passed; its own headline says from $499

Check PlushCare pricing Read the full PlushCare review

NuDay Rx

Shoppers who want both compounded and brand-name GLP-1 options with a named pharmacy on one platform.

Reasons to consider it

Named compounding pharmacy (Belmar Pharmacy) and named prescriber network (Beluga Health) — both independently verifiable
Displays a LegitScript verification badge
Both injectable and oral-tablet forms available for semaglutide and tirzepatide, plus a full brand-name menu on the same account

What to weigh up

Compounded semaglutide ($249) and tirzepatide ($329) are priced above several budget competitors in this comparison set
Oral tirzepatide tablets ($399/mo) cost more than the injectable compound form ($329/mo) — a naive assumption that oral is cheaper or equivalent would be wrong here
No state-by-state availability list is published — only a general note about shipping availability

Compounded drugs are not FDA-approved. Understand the medication options.

Check NuDay Rx pricing Read the full NuDay Rx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

PlushCareNuDay Rx

Normalized Cost/Month: PlushCare:
27/100; NuDay Rx:
48/100

Price Transparency: PlushCare:
64/100; NuDay Rx:
86/100

Nationwide Access: PlushCare:
86/100; NuDay Rx:
24/100

Formulation Options: PlushCare:
79/100; NuDay Rx:
90/100

Clinical Oversight: PlushCare:
82/100; NuDay Rx:
75/100

Contract Flexibility: PlushCare:
41/100; NuDay Rx:
47/100

Before you sign up

Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.