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Head-to-head · Cost-Efficiency Index

Options Medical Weight Loss vs RxPepsDirect

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #255

Options Medical Weight Loss

Patients near one of its 27 physical clinic locations across PA, AZ, IL, MI, OH, FL, GA, IN, or NC who prefer in-person obesity-medicine care over telehealth.

Visit Options Medical Weight Loss
VS
Grade C · #256

RxPepsDirect

Cost-first shoppers who want the all-in per-order cost of a compounded GLP-1 with no subscription, in 28 states.

Visit RxPepsDirect

The verdict

Too close to callGrade C vs C

Options Medical Weight Loss and RxPepsDirect tie on the Cost-Efficiency Index at 60/100, so neither wins outright on the numbers. For most shoppers we'd start with Options Medical Weight Loss (ranked #255, a hair above #256) — Patients near one of its 27 physical clinic locations across PA, AZ, IL, MI, OH, FL, GA, IN, or NC who prefer in-person obesity-medicine care over telehealth. But RxPepsDirect is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Options Medical Weight Loss.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

55
83

Price Transparency

78
30

Nationwide Access

24
52

Formulation Options

66
66

Clinical Oversight

88
70

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecOptions Medical Weight LossRxPepsDirect
Cost-Efficiency Index60/10060/100
Semaglutide / mo$199/mo (starting dose, compounded)$79/mo (starting dose, visit fee and shipping included, compounded)
Tirzepatide / mo$399/mo (starting dose, compounded)$99/mo (starting dose, visit fee and shipping included, compounded)
Semaglutide / yr (modeled)$2,388$948
Tirzepatide / yr (modeled)$4,788$1,188
CoverageCoverage not published28 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#255#256

Options Medical Weight Loss

60/100

Where the value is

  • Rare in-person clinic model with ABOM (obesity-medicine board) certified providers
  • LegitScript certified and Newsweek-recognized
  • Medication included in the advertised monthly price, not billed separately

The tradeoffs

  • Only available in 9 states with in-person locations, heavily concentrated in Illinois and Ohio
  • 'Starting at' prices are for the lowest dose only; real cost at higher/maintenance doses not disclosed
Visit Options Medical Weight Loss

Full Options Medical Weight Loss review →

RxPepsDirect

60/100

Where the value is

  • Every component of the price is published on the site — the vial tiers, the flat visit charge and the flat overnight delivery — so the all-in monthly cost can be worked out before ordering
  • No subscription and no commitment: you pay per order, and one visit charge covers up to three peptides on the same prescription
  • Real 503A telehealth Rx — licensed NP/PA prescribers under medical director Dr. Jonathan Snipes (NPI 1821250077), dispensed by Optimal Balance Pharmacy, Texas Ranking #34829

The tradeoffs

  • The advertised vial price is not the monthly cost: a flat $39 medical visit charge and $15 flat FedEx shipping land on every order, and the visit charge recurs on every reorder rather than once
  • Higher doses need more than one vial a month and the site publishes no price for the dose you titrate up to, so the figure above is a floor
Visit RxPepsDirect

Full RxPepsDirect review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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