Head-to-head · Cost-Efficiency Index
OnlyRx vs Shapely
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
OnlyRx
Shoppers who want a 50-state marketplace with multiple pharmacy options and named prescribers.
Visit OnlyRxShapely
Cost-first shoppers who want insured patients in CA, FL, NY, or TX who want help navigating coverage for branded GLP-1s.
Visit ShapelyThe verdict
OnlyRx and Shapely tie on the Cost-Efficiency Index at 64/100, so neither wins outright on the numbers. For most shoppers we'd start with OnlyRx (ranked #180, a hair above #182) — Shoppers who want a 50-state marketplace with multiple pharmacy options and named prescribers. But Shapely is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs OnlyRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | OnlyRx | Shapely |
|---|---|---|
| Cost-Efficiency Index | 64/100 | 64/100 |
| Semaglutide / mo | $179/mo (starting dose, compounded) | $99/mo (plus a separate fee, compounded) |
| Tirzepatide / mo | $249/mo (starting dose, compounded) | $166/mo (plus a separate fee, compounded) |
| Semaglutide / yr (modeled) | $2,148 | $1,188 |
| Tirzepatide / yr (modeled) | $2,988 | $1,992 |
| Coverage | Coverage not published | 4 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Yes | Yes |
| Rank here | #180 | #182 |
OnlyRx
64/100Where the value is
- Serves all 50 states per its own claim, wider than most compounded-GLP-1 competitors
- Two named prescribers with published NPI numbers (Dr. Ana Lisa Carr, Dr. Kelly Tenbrink), plus two supporting providers
- Sources medication from four named, recognizable 503A-style pharmacy partners rather than one undisclosed source
The tradeoffs
- The $179 headline price is explicitly labeled a 'Summer Promo' on the site's own homepage — no post-promo price is published
- No dose-tier (mg) breakdown is published for any of the four price points
Shapely
64/100Where the value is
- Named, credentialed founder (Dr. Justin Zaghi, Harvard-trained, board-certified obesity medicine)
- Genuine insurance-navigation service across 8 major payers, potentially large savings if covered
- Both cash-pay compounded and insurance-covered branded pathways offered
The tradeoffs
- Live in only 4 states (CA, FL, NY, TX) despite a '50-state expansion' announcement
- Separate membership fee stacks on top of medication cost, and its headline prices ($9 first month, $49/mo promo) are not the real ongoing rate ($99/mo)
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.