Head-to-head · Cost-Efficiency Index
NuviaRx vs Zeuss
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
NuviaRx
Cost-first shoppers who want the lowest 'starting' price on paper, if you're willing to prepay a full year.
Visit NuviaRxZeuss
Patients already stable on a maintenance GLP-1 dose who want to pay per fill instead of a subscription.
Visit ZeussThe verdict
NuviaRx takes it, leading the Cost-Efficiency Index 64 to 63. NuviaRx is a compounded GLP-1 telehealth platform advertising semaglutide from $140/mo and tirzepatide from $170/mo, but both figures require purchasing a full annual plan upfront no month-to-month pricing is published anywhere on the site. Zeuss still earns a C — Patients already stable on a maintenance GLP-1 dose who want to pay per fill instead of a subscription.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs NuviaRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | NuviaRx | Zeuss |
|---|---|---|
| Cost-Efficiency Index | 64/100 | 63/100 |
| Semaglutide / mo | $140/mo (all doses, annual plan, compounded) | $125/mo (starting dose, compounded) |
| Tirzepatide / mo | $170/mo (all doses, compounded) | $175/mo (starting dose, compounded) |
| Semaglutide / yr (modeled) | $1,680 | $1,500 |
| Tirzepatide / yr (modeled) | $2,040 | $2,100 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Yes |
| Rank here | #179 | #186 |
NuviaRx
64/100Where the value is
- Genuinely flat pricing across all doses within the annual plan, with consultation and monthly check-ins bundled in
- No membership fees or dose-escalation surcharges disclosed
- Free home delivery included; cancel-anytime language present despite the annual-prepay framing
The tradeoffs
- The advertised '$140/$170 starting' price is gated behind a full annual prepay — no month-to-month rate is published anywhere on the site, so the headline figure is not accessible the way it reads
- No compounding pharmacy is named — only described generically as 'a licensed 503A compounding pharmacy'
Zeuss
63/100Where the value is
- Genuinely no-subscription billing confirmed in its own FAQ ('no recurring charges or automatic refills') — patients pay per order, not a locked recurring plan
- LegitScript certified, with the badge and verification link displayed on the homepage
- States it 'partners exclusively with 503A and 503B state-licensed compounding pharmacies'
The tradeoffs
- Both $125 and $175 are 'starting at' prices with no disclosed dose (mg) or confirmation the price holds at higher/titrated doses
- No compounding pharmacy is named, only 'licensed partner pharmacy'
Regulatory note: the FDA issued a warning letter to Zeuss LLC dba Zeuss in February 2026. We still list and link to Zeuss; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.