Head-to-head · Cost-Efficiency Index
Nucore Health vs TelePeptide
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Nucore Health
Shoppers who want a single flat monthly price regardless of dose and don't need tirzepatide.
Visit Nucore HealthTelePeptide
Cost-first shoppers who want all-in compounded GLP-1 from $169/mo; LegitScript-certified, 48 states.
Visit TelePeptideThe verdict
Nucore Health and TelePeptide tie on the Cost-Efficiency Index at 55/100, so neither wins outright on the numbers. For most shoppers we'd start with Nucore Health (ranked #341, a hair above #348) — Shoppers who want a single flat monthly price regardless of dose and don't need tirzepatide. But TelePeptide is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Nucore Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Nucore Health | TelePeptide |
|---|---|---|
| Cost-Efficiency Index | 55/100 | 55/100 |
| Semaglutide / mo | $299/mo (all doses, compounded) | $199/mo (starting dose, annual plan, compounded oral) |
| Tirzepatide / mo | Not disclosed | $219/mo (starting dose, annual plan, compounded oral) |
| Semaglutide / yr (modeled) | $3,588 | $2,388 |
| Tirzepatide / yr (modeled) | — | $2,628 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #341 | #348 |
Nucore Health
55/100Where the value is
- Flat $299/month price for semaglutide regardless of dose tier, easy to budget
- LegitScript certification badge displayed
- Claims nationwide coverage across all 50 states
The tradeoffs
- No tirzepatide pricing found
- Named pharmacy partner (Fullscript) is atypical for compounded injectables, unclear who actually fulfills the semaglutide prescription
TelePeptide
55/100Where the value is
- LegitScript-certified (seal ID 49966407); 503A-licensed compounding pharmacies
- All-inclusive from $169/mo annual — physician eval + Rx + medication + shipping, no hidden fees
- Broadest formulation menu: injectable sema/tirz, oral dissolvable tablets, sema+naltrexone, microdose combos
The tradeoffs
- Compounded medications are not FDA-approved; no pharmacy partner named publicly
- Monthly billing costs more — $199/mo (monthly) vs $169/mo (annual) for semaglutide injectable; best rate requires annual prepay
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.