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Head-to-head · Cost-Efficiency Index

Nova vs Queen RX

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #78

Nova

Readers who want the membership inside the quoted price rather than added to it, and who want a daily sublingual option beside the injection.

Visit Nova
VS
Grade C · #82

Queen RX

Cost-first shoppers who want a low one-time cost to try a GLP-1 without committing to a monthly subscription.

Visit Queen RX

The verdict

Winner · NovaGrade C vs C

Nova takes it, leading the Cost-Efficiency Index 72 to 71. Nova (trynova.co) bundles the medication, refrigerated shipping and a $99 monthly membership into one figure — $198 for semaglutide and $210 for tirzepatide — and serves 49 states, everywhere except California. Queen RX still earns a CCost-first shoppers who want a low one-time cost to try a GLP-1 without committing to a monthly subscription.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Nova.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

58
65

Price Transparency

78
78

Nationwide Access

78
78

Formulation Options

77
71

Clinical Oversight

73
70

Contract Flexibility

73
61

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNovaQueen RX
Cost-Efficiency Index72/10071/100
Semaglutide / mo$198/mo month-to-month all-in (medication plus the $99/mo membership; a "Starting at" floor that rises with dose)$100/mo (starting dose, bundle, compounded)
Tirzepatide / mo$210/mo month-to-month all-in (same bundle; also a "Starting at" floor)$100/mo (bundle, compounded)
Semaglutide / yr (modeled)$2,376$1,200
Tirzepatide / yr (modeled)$2,520$1,200
Coverage49 states45 states
Oral / sublingualYesNo
Brand-name accessCompounded onlyCompounded only
Rank here#78#82

Nova

72/100

Where the value is

  • Quotes one all-in figure that already contains the $99 monthly membership, the medication and refrigerated shipping, so the membership is not a surprise at checkout
  • Names a medical director and a nurse practitioner with credentials, training and residency detail
  • Prices a daily oral route for both molecules alongside the weekly injections

The tradeoffs

  • Three sets of prices are live at once: $198 and $210 in the hero, $229 and $279 in the same pages' own FAQ headings, and a third set in the site's JavaScript
  • The FAQ's own arithmetic does not reach the headline — $99 membership plus $130 medication is $229, not the $198 quoted above it
Visit Nova

Full Nova review →

Queen RX

71/100

Where the value is

  • Full refund if the physician determines you can't be prescribed anything
  • No subscription or membership fee — a single $299 purchase covers a full 3-month course including supplies
  • Works out to one of the lower per-month equivalents in this batch when averaged over the 3-month term

The tradeoffs

  • Not actually a monthly price — it's a one-time $299 purchase per 3-month term; there is no month-to-month billing option at all
  • No price differentiation between semaglutide, tirzepatide, and liraglutide — all fall under the same $299 bundle regardless of which drug is prescribed or its dose
Visit Queen RX

Full Queen RX review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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