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Head-to-head · Cost-Efficiency Index

Nova MD vs YourHealthRx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #254

Nova MD

Shoppers who want an explicit tirzepatide dose-titration schedule alongside tiered pricing.

Visit Nova MD
VS
Grade C · #260

YourHealthRx

Cost-first shoppers who want science-forward GLP-1 and peptide care, flat-rate dosing, built-in follow-up.

Visit YourHealthRx

The verdict

Too close to callGrade C vs C

Nova MD and YourHealthRx tie on the Cost-Efficiency Index at 60/100, so neither wins outright on the numbers. For most shoppers we'd start with Nova MD (ranked #254, a hair above #260) — Shoppers who want an explicit tirzepatide dose-titration schedule alongside tiered pricing. But YourHealthRx is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Nova MD.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

53
53

Price Transparency

78
30

Nationwide Access

24
86

Formulation Options

79
77

Clinical Oversight

88
88

Contract Flexibility

47
33

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNova MDYourHealthRx
Cost-Efficiency Index60/10060/100
Semaglutide / mo$175/mo (compounded)$170/mo (compounded)
Tirzepatide / mo$199/mo (compounded)$210/mo (compounded)
Semaglutide / yr (modeled)$2,100$2,040
Tirzepatide / yr (modeled)$2,388$2,520
CoverageCoverage not publishedAll 50 states
Oral / sublingualNoYes
Brand-name accessYesCompounded only
Rank here#254#260

Nova MD

60/100

Where the value is

  • Full 1/3/6/12-month tirzepatide pricing ladder disclosed, down to $149/mo on the annual plan
  • Explicit monthly dose-titration schedule published for tirzepatide (2.5mg to 15mg over 6 months) — more clinical detail than most competitors in this set show
  • LegitScript verification badge present with a working link to legitscript.com

The tradeoffs

  • No compounding pharmacy is named — only 'Licensed U.S. Pharmacy'
  • No state-coverage list is published anywhere on the public site (checked homepage, medical-disclaimers, and refund-policy pages)
Visit Nova MD

Full Nova MD review →

YourHealthRx

60/100

Where the value is

  • Available in all 50 states and DC through a multi-state (IMLC) licensed clinician network
  • Compounded semaglutide and tirzepatide in two formats - weekly injectable (with B12) or daily oral dissolving tablet
  • Flat subscription price that doesn't change as your dose increases (no titration penalty)

The tradeoffs

  • Eligibility and prescribing run through partner clinical workflows - YourHealthRx is the platform, not the prescriber or pharmacy
  • Compounded medications are not FDA-approved - not brand Wegovy, Ozempic, Zepbound, or Mounjaro
Visit YourHealthRx

Full YourHealthRx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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