Head-to-head · Cost-Efficiency Index
Nolu vs OrderlyMeds
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Nolu
Shoppers who want GLP-1 plus an adjacent microdose or NAD+/longevity line without juggling separate accounts.
Visit NoluOrderlyMeds
Cost-first shoppers who want a first GLP-1 course at a published starter rate, with the standing rate published beside it.
Visit OrderlyMedsThe verdict
Nolu and OrderlyMeds tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers. For most shoppers we'd start with Nolu (ranked #111, a hair above #112) — Shoppers who want GLP-1 plus an adjacent microdose or NAD+/longevity line without juggling separate accounts. But OrderlyMeds is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Nolu.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Nolu | OrderlyMeds |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $249 (billed per 4 weeks, ~8% above nominal monthly) | $74/mo (starting dose, 2-mo starter plan, new patients only, compounded) |
| Tirzepatide / mo | $339 (billed per 4 weeks, ~8% above nominal monthly) | $299/mo (compounded) |
| Semaglutide / yr (modeled) | $2,988 | $888 |
| Tirzepatide / yr (modeled) | $4,068 | $3,588 |
| Coverage | All 50 states + Washington, D.C. (standard eligibility hedge) | Coverage not published |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #111 | #112 |
Nolu
68/100Where the value is
- Both molecules published up front — $249 semaglutide, $339 tirzepatide — plus an oral semaglutide tablet option
- All-inclusive per-cycle pricing: consultation, medication and shipping bundled, no separate membership fee
- LegitScript verified
The tradeoffs
- Billed every 4 weeks, not per calendar month — 13 charges a year, not 12, so the real annualized cost runs ~8% above the headline figure
- No named medical director, prescriber, or compounding pharmacy disclosed anywhere on the site
OrderlyMeds
68/100Where the value is
- The starter rate and the standing rate are both published, so the step-up is visible before signing up
- No membership fees and no hidden costs, stated as such
- The dose ladder is published: four weeks at 0.25 mg then four weeks at 0.5 mg
The tradeoffs
- The $74 rate is a two-month starter plan billed as $149 up front, and it is open only to patients new to GLP-1 medication; the standing monthly rate is $149
- Tirzepatide has no equivalent standing discount — $299/mo is the ongoing rate
Regulatory note: the FDA issued a warning letter to OrderlyMeds LLC dba OrderlyMeds in June 2026. We still list and link to OrderlyMeds; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.