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Head-to-head · Cost-Efficiency Index

Nolu vs JumpstartMD

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #111

Nolu

Shoppers who want GLP-1 plus an adjacent microdose or NAD+/longevity line without juggling separate accounts.

Visit Nolu
VS
Grade C · #118

JumpstartMD

Cost-first shoppers who want california residents who want an established in-person clinic option with telehealth backup, prescribing brand-name (not compounded) GLP-1s.

Visit JumpstartMD

The verdict

Too close to callGrade C vs C

Nolu and JumpstartMD tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers. For most shoppers we'd start with Nolu (ranked #111, a hair above #118) — Shoppers who want GLP-1 plus an adjacent microdose or NAD+/longevity line without juggling separate accounts. But JumpstartMD is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Nolu.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

58
74

Price Transparency

72
78

Nationwide Access

90
42

Formulation Options

78
79

Clinical Oversight

55
80

Contract Flexibility

78
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecNoluJumpstartMD
Cost-Efficiency Index68/10068/100
Semaglutide / mo$249 (billed per 4 weeks, ~8% above nominal monthly)$107/mo (starting dose, brand-name)
Tirzepatide / mo$339 (billed per 4 weeks, ~8% above nominal monthly)$173/mo (starting dose, plus a separate fee, brand-name)
Semaglutide / yr (modeled)$2,988$1,284
Tirzepatide / yr (modeled)$4,068$2,076
CoverageAll 50 states + Washington, D.C. (standard eligibility hedge)1 state
Oral / sublingualYesNo
Brand-name accessCompounded onlyYes
Rank here#111#118

Nolu

68/100

Where the value is

  • Both molecules published up front — $249 semaglutide, $339 tirzepatide — plus an oral semaglutide tablet option
  • All-inclusive per-cycle pricing: consultation, medication and shipping bundled, no separate membership fee
  • LegitScript verified

The tradeoffs

  • Billed every 4 weeks, not per calendar month — 13 charges a year, not 12, so the real annualized cost runs ~8% above the headline figure
  • No named medical director, prescriber, or compounding pharmacy disclosed anywhere on the site
Visit Nolu

Full Nolu review →

JumpstartMD

68/100

Where the value is

  • Long-established, well-known clinic chain with real physical locations, not just a telehealth storefront
  • Prescribes FDA-approved BRANDED medications rather than compounded versions
  • LegitScript seal confirmed in footer

The tradeoffs

  • Geographically limited -- essentially California/Bay-Area only for in-person care
  • Combined membership + medication pricing structure makes true cost comparison harder
Visit JumpstartMD

Full JumpstartMD review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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