Head-to-head · Cost-Efficiency Index
NiceRx vs ReflexMD
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
NiceRx
Cost-first shoppers who want a clearly disclosed standing month-to-month rate rather than a prepay-gated one.
Visit NiceRxReflexMD
Shoppers who want one flat monthly price that won't rise with the dose and who are comfortable canceling by phone.
Visit ReflexMDThe verdict
NiceRx takes it, leading the Cost-Efficiency Index 76 to 75. NiceRx is a compounded GLP-1 telehealth platform charging $199/mo for semaglutide and $299/mo for tirzepatide on an ongoing month-to-month basis (first month discounted to $99 and $199 respectively). ReflexMD still earns a C — Shoppers who want one flat monthly price that won't rise with the dose and who are comfortable canceling by phone.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs NiceRx.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | NiceRx | ReflexMD |
|---|---|---|
| Cost-Efficiency Index | 76/100 | 75/100 |
| Semaglutide / mo | $199/moAll doses, compounded | $297/moCompounded, same price at every dose, month to month |
| Tirzepatide / mo | $299/moAll doses, compounded | $367/moCompounded, same price at every dose, month to month |
| Semaglutide / yr (modeled) | $2,388 | $3,564 |
| Tirzepatide / yr (modeled) | $3,588 | $4,404 |
| Coverage | 46 states | All 50 states |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #64 | #69 |
NiceRx
76/100Where the value is
- Explicitly discloses both the promotional first-month price and the real ongoing 'every month thereafter' rate on the same page, rather than only advertising the promo
- Flat pricing across all doses, with the provider visit and shipping bundled into the price
- Cancel-anytime billing with no long-term commitment
The tradeoffs
- Not available in Alaska, Mississippi, New Jersey, or Kansas
- Compounded only — no FDA-approved brand option
ReflexMD
75/100Where the value is
- Both prices are shown on the homepage before any quiz, and the site calls them flat-rate pricing
- The online consultation fee is included in the subscription, and shipping is free and overnight once the pharmacy ships
- Month to month with no long-term contract; 3- and 6-month plans are optional, with 15% off 3-month plans under a current promo code
The tradeoffs
- Outside California you must call to cancel, at least two days before the renewal date; California residents can also cancel by email
- Fees already paid are not refunded once the month is billed
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.