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Head-to-head · Cost-Efficiency Index

Luci vs ZYP Medical

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #326

Luci

Patients willing to commit to and prepay a full 12-month plan for the lowest advertised rate.

Visit Luci
VS
Grade C · #333

ZYP Medical

Cost-first shoppers who want men in IA, NE, SD, MN, KS, CO or AZ wanting a low starter rate with an oral needle-free option.

Visit ZYP Medical

The verdict

Too close to callGrade C vs C

Luci and ZYP Medical tie on the Cost-Efficiency Index at 56/100, so neither wins outright on the numbers. For most shoppers we'd start with Luci (ranked #326, a hair above #333) — Patients willing to commit to and prepay a full 12-month plan for the lowest advertised rate. But ZYP Medical is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Luci.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

77
37

Price Transparency

30
64

Nationwide Access

24
42

Formulation Options

90
77

Clinical Oversight

72
78

Contract Flexibility

47
53

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecLuciZYP Medical
Cost-Efficiency Index56/10056/100
Semaglutide / mo$99/mo (starting dose, 12-month plan, compounded)$150/mo (starting dose, 3 month plan, plus a separate fee, compounded)
Tirzepatide / mo$145/mo (starting dose, 12-month plan, compounded)$233/mo (starting dose, 3 month plan, plus a separate fee, compounded)
Semaglutide / yr (modeled)$1,188$1,800
Tirzepatide / yr (modeled)$1,740$2,796
CoverageCoverage not published6 states
Oral / sublingualYesYes
Brand-name accessYesCompounded only
Rank here#326#333

Luci

56/100

Where the value is

  • Offers both semaglutide and tirzepatide
  • Named clinical/telehealth partner (DrTelx) rather than zero disclosure
  • Clear brand positioning (women-focused weight loss)

The tradeoffs

  • Headline 'as low as' prices are explicitly 12-month-prepay-only, with true monthly cost never disclosed
  • States-served list is incomplete ('CA, FL, and others')
Visit Luci

Full Luci review →

ZYP Medical

56/100

Where the value is

  • Offers a genuine needle-free oral tirzepatide (ODT) option, not just injectable
  • Consult fee is disclosed and itemized ($50, or $29.99 for a shorter returning-patient visit)
  • Recently expanded to 7 states (added Minnesota)

The tradeoffs

  • Advertised $150/$233 prices are explicitly labeled 'starter plans (initial 3 months)' — what they become after 3 months is not published anywhere on the site
  • One-time consult fee ($29.99-$50) is charged on top of the medication price and is non-refundable once the visit occurs
Visit ZYP Medical

Full ZYP Medical review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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