Head-to-head · Cost-Efficiency Index
Lttl vs 24hrDOC
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Lttl
Shoppers who want every commitment tier priced openly before intake, and who will read which rung the headline came from.
Visit Lttl24hrDOC
Shoppers comparing the ongoing standing price of compounded GLP-1s, not the first-month promotional rate.
Visit 24hrDOCThe verdict
24hrDOC takes it, leading the Cost-Efficiency Index 57 to 55. 24hrDOC is a fast, cash-pay telehealth service selling compounded semaglutide and tirzepatide, both as standard weekly injections and as lower-cost nightly/daily microdose options. Lttl still earns a C — Shoppers who want every commitment tier priced openly before intake, and who will read which rung the headline came from.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs 24hrDOC.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Lttl | 24hrDOC |
|---|---|---|
| Cost-Efficiency Index | 55/100 | 57/100 |
| Semaglutide / mo | $199/mo (compounded) | $249/mo (microdose tier, 2 mg dose, compounded) |
| Tirzepatide / mo | $279/mo (compounded) | $339/mo (microdose tier, starting dose, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,988 |
| Tirzepatide / yr (modeled) | $3,348 | $4,068 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #295 | #296 |
Lttl
55/100Where the value is
- Publishes the full price matrix — every medication, form and commitment length — on a public /plans page before checkout, including the literal "$279/mo every month"
- Named medical advisory board (pharmacist, nurse practitioner, physical therapist) rather than zero disclosure
- Real LegitScript verification badge with a working certificate link
The tradeoffs
- Headline marketing price is a 12-month-prepay rate, not the true month-to-month cost — "Plans start at $129/mo" is $1,548 paid up front
- True cancel-anytime price is $199 semaglutide and $279 tirzepatide, 35–40% above the advertised "from" figures
24hrDOC
57/100Where the value is
- Full struck-through pricing (promo vs. regular) is published on-site before intake, so the true ongoing cost is verifiable rather than hidden
- Both standard and lower-cost microdose options published for each drug
- Fast intake model: '10-minute assessment' with no office visit required
The tradeoffs
- The widely-advertised $149/$239 price is a ONE-TIME first-month discount ('$100 off'); the standing ongoing price is $249/mo semaglutide and $339/mo tirzepatide — about 40% higher
- No compounding pharmacy or medical director named on the site
Regulatory note: the FDA issued a warning letter to 24HrDoc, Inc. dba 24HrDoc in February 2026. We still list and link to 24hrDOC; you should know the letter is on the public record before you decide.
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.