Head-to-head · Cost-Efficiency Index
Loop Health vs YourEra
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Loop Health
Cost-first shoppers who want peptide and wellness membership with GLP-1s as one offering.
Visit Loop HealthYourEra
Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Visit YourEraThe verdict
Loop Health takes it, leading the Cost-Efficiency Index 65 to 62. Loop Health is a US telehealth membership platform offering compounded semaglutide and tirzepatide under its Loop Lean program, alongside peptides, NAD+, sermorelin, coaching, and bloodwork. YourEra still earns a C — Shoppers chasing the lowest sticker price who will verify what's actually billed after the first month.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Loop Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Loop Health | YourEra |
|---|---|---|
| Cost-Efficiency Index | 65/100 | 62/100 |
| Semaglutide / mo | $199/mo (all doses, microdosed, membership required, compounded) | $179/mo (all doses, month-to-month, compounded) |
| Tirzepatide / mo | $299/mo (all doses, microdosed, membership required, compounded) | $259/mo (all doses, month-to-month, compounded) |
| Semaglutide / yr (modeled) | $2,388 | $2,148 |
| Tirzepatide / yr (modeled) | $3,588 | $3,108 |
| Coverage | All 50 states | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #164 | #171 |
Loop Health
65/100Where the value is
- Multi-product wellness platform — GLP-1 plus peptides, NAD+, coaching, bloodwork
- Low membership entry point ($79/mo)
- Annual plan includes monthly 'research credit' toward compounds
The tradeoffs
- The medication price is on top of a $1,500-a-year membership, annual-plan only, which the terms confirm is separate from compound and medication costs
- Everything sold here is microdosed — the banner over both products reads 'MICRODOSED GLP-1', which is not a labeled therapeutic dose
YourEra
62/100Where the value is
- A 6-month prepay drops semaglutide to $99/month, among the lowest compounded-GLP-1 headline prices we track
- No membership-fee structure; the site markets "no hidden fees" and "Same price at every dose"
- Prescriptions are "issued only if deemed medically appropriate" after evaluation by licensed US clinicians, stated plainly
The tradeoffs
- The advertised $99/month requires a 6-month prepay — paying month to month costs $149 for the first month and $179/month after, nearly double the headline
- Tirzepatide's advertised $179 is a first-month intro, not a prepay rung: the page's own words are "Month-to-month intro. Then $259/mo." — so the two molecules' headline discounts work in two different ways on one page
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.