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WeighLab

Lean Meds vs NiceRx

Compare the prices, treatment options and tradeoffs that matter before you choose a GLP-1 program.

By The WeighLab Bench. Provider verification dates appear below.

Lean Meds

Provider comparison

Cost-first shoppers who want a genuinely flat all-dose price and named pharmacies, and who will read the $49 headline as the annual plan it is.

Semaglutide / month
$79/moMonth-to-month, flat at every dose (the advertised $49 is the 12-month plan)
Tirzepatide / month
$109/moMonth-to-month, flat at every dose (the advertised $95 is the 12-month plan)
Index 84/100 · Grade BChecked September 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check Lean Meds pricing Read review

NiceRx

Provider comparison

Cost-first shoppers who want a clearly disclosed standing month-to-month rate rather than a prepay-gated one.

Semaglutide / month
$149 per 4 weeksAll doses, compounded
Tirzepatide / month
$249 per 4 weeksAll doses, compounded
Index 82/100 · Grade B−Checked October 2026

Compounded drugs are not FDA-approved. Understand the medication options.

Check NiceRx pricing Read review

We may earn a commission if you sign up through a provider link, at no extra cost to you. Compensation does not change scores. How we earn money.

The comparison in brief

Lean Meds has the higher Cost-Efficiency Index: 84/100 versus 82/100. That is a value comparison under our published methodology, not a measure of medical suitability or a guarantee of results.

Check the difference in state access

Lean Meds
All 50 states
NiceRx
46 states

The better fit depends on what is included in your quote. A lower advertised price can require prepayment, apply to a starting dose or leave out a separate fee.

How the comparison is scored

Costs & coverage

Published prices with their terms intact. Annual estimates account for billing frequency and known fixed required fees; they are not a treatment quote.

Lean Meds

NiceRx

Semaglutide / month
Lean Meds: $79/moMonth-to-month, flat at every dose (the advertised $49 is the 12-month plan)
NiceRx: $149 per 4 weeksAll doses, compounded
Tirzepatide / month
Lean Meds: $109/moMonth-to-month, flat at every dose (the advertised $95 is the 12-month plan)
NiceRx: $249 per 4 weeksAll doses, compounded
Semaglutide / year (modeled)
Lean Meds: $948
NiceRx: $1,93713 charges
Tirzepatide / year (modeled)
Lean Meds: $1,308
NiceRx: $3,23713 charges
State availability
Lean Meds: All 50 states
NiceRx: 46 states
Oral / sublingual option listed
Lean Meds: Not listed
NiceRx: Not listed
Brand-name access listed
Lean Meds: Not confirmed
NiceRx: Not confirmed
Provider facts checked
Lean Meds: September 2026
NiceRx: October 2026

Comparing different billing plans? See what a GLP-1 monthly price can leave out, or calculate the monthly cost.

Which program fits your priorities?

The strengths and limitations behind each provider's score. Read the full review before deciding.

Lean Meds

Cost-first shoppers who want a genuinely flat all-dose price and named pharmacies, and who will read the $49 headline as the annual plan it is.

Reasons to consider it

  • A flat rate at every dose on both molecules, stated as such, so the price does not climb as a provider titrates
  • Names all four pharmacies in its network with addresses, phone numbers and websites, and states the 503A designation in the footer of every page
  • The full four-rung ladder for each molecule is printed on one page, so a reader can see what a commitment actually saves

What to weigh up

  • The homepage sells "Starting at $49/mo — same price every month, first order and every order after"; $49 is the twelve-month semaglutide plan and the month-to-month rate is $79
  • A homepage chip reads "No auto rebill" while the terms say the payment method is automatically charged at recurring intervals until you cancel
  • Every offer page runs a countdown reading "Price increases in" with no dated deadline behind it

Compounded drugs are not FDA-approved. Understand the medication options.

Check Lean Meds pricing Read the full Lean Meds review

NiceRx

Cost-first shoppers who want a clearly disclosed standing month-to-month rate rather than a prepay-gated one.

Reasons to consider it

  • Public prices for each plan length
  • Provider review, medication and delivery included
  • Names Nice Health medical groups and six pharmacy partners

What to weigh up

  • Four-week billing means 13 charges over 52 weeks
  • Lower headline averages require 12-, 24- or 48-week prepayment
  • Generic pricing-page monthly language conflicts with the explicit product billing intervals

Compounded drugs are not FDA-approved. Understand the medication options.

Check NiceRx pricing Read the full NiceRx review

Explore the six scoring factors

Scores run from 0 to 100. A higher factor score reflects our published value criteria; it is not a clinical endorsement.

Lean MedsNiceRx
Normalized Cost/Month
Lean Meds:
97/100
NiceRx:
85/100
Price Transparency
Lean Meds:
97/100
NiceRx:
97/100
Nationwide Access
Lean Meds:
86/100
NiceRx:
78/100
Formulation Options
Lean Meds:
66/100
NiceRx:
66/100
Clinical Oversight
Lean Meds:
73/100
NiceRx:
91/100
Contract Flexibility
Lean Meds:
67/100
NiceRx:
67/100

Before you sign up

  • Confirm your totalAsk about dose changes, membership, labs, shipping and cancellation terms.
  • Check treatment accessState coverage and medical eligibility can differ by medication and formulation.
  • Understand the medicationCompare compounded and brand-name options. Compounded drugs are not FDA-approved.

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Provider information reflects public disclosures at the verification dates shown. Prices and availability change; confirm current terms before paying. This comparison is for information, not medical advice. A licensed clinician determines whether treatment is appropriate.