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Head-to-head · Cost-Efficiency Index

Invigor Medical vs Synergy Rx

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade B+ · #2

Invigor Medical

Value shoppers who want competitive pricing on both molecules plus a wider wellness/hormone program on one account.

Visit Invigor Medical
VS
Grade C · #31

Synergy Rx

People who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by enquiry.

Visit Synergy Rx

The verdict

Winner · Invigor MedicalGrade B+ vs C

Invigor Medical takes it, leading the Cost-Efficiency Index 88 to 71. Solid mid-market cost on both molecules from an established operator — good value if you also want a broader metabolic and hormone catalog. Synergy Rx still earns a CPeople who want a genuine brand-name route and maximum clinician access, and will accept getting a quote by enquiry.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the board). See how it stacks up: CoreAge Rx vs Invigor Medical.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

86
70

Price Transparency

84
52

Nationwide Access

78
62

Formulation Options

82
84

Clinical Oversight

86
90

Contract Flexibility

87
68

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecInvigor MedicalSynergy Rx
Cost-Efficiency Index88/10071/100
Semaglutide / mo$199/moFrom $199/mo
Tirzepatide / mo$339/moFrom $349/mo
Semaglutide / yr (modeled)$2,388$2,388
Tirzepatide / yr (modeled)$4,068$4,188
CoverageNot disclosedNot disclosed
Oral / sublingualNoNo
Brand-name accessCompounded onlyYes
Rank on the board#2#31

Invigor Medical

88/100

Where the value is

  • Competitive mid-market pricing on both semaglutide and tirzepatide
  • Long-running operator with a broad catalog that can consolidate spend
  • Both molecules published up front for easy cost modeling

The tradeoffs

  • Does not publish an explicit states-served list, so access is a variable in the model
  • Compounded only
Visit Invigor Medical

Full Invigor Medical review →

Synergy Rx

71/100

Where the value is

  • Prescribes FDA-approved brand Wegovy, Ozempic and Mounjaro when clinically appropriate, not compounded only
  • Unlimited appointments, unlimited messaging and 24/7 access to a dedicated clinical team
  • A $100 welcome credit applied at checkout, and FSA/HSA eligible

The tradeoffs

  • Publishes no GLP-1 price anywhere on its own site, so total cost cannot be modelled before an enquiry
  • At $349/mo tirzepatide sits roughly $100 above the compounded median we track
Visit Synergy Rx

Full Synergy Rx review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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