Head-to-head · Cost-Efficiency Index
Harper Meds vs RxPros
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Harper Meds
Cost-first shoppers who want a genuinely all-in flat price with a disclosed operating entity and physician networks.
Visit Harper MedsRxPros
Shoppers who want the lowest ongoing per-month compounded rate and don't mind a higher-priced first order.
Visit RxProsThe verdict
Harper Meds and RxPros tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers. For most shoppers we'd start with Harper Meds (ranked #113, a hair above #120) — Cost-first shoppers who want a genuinely all-in flat price with a disclosed operating entity and physician networks. But RxPros is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Harper Meds.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Harper Meds | RxPros |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $149/mo | $100/mo (all doses, compounded) |
| Tirzepatide / mo | $196/mo | $145/mo (all doses, compounded) |
| Semaglutide / yr (modeled) | $1,788 | $1,200 |
| Tirzepatide / yr (modeled) | $2,352 | $1,740 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #113 | #120 |
Harper Meds
68/100Where the value is
- Genuinely all-inclusive pricing ('ONE PRICE for everything: doctor consultation, prescription, 4 weeks of medication & free shipping'), not a bare medication cost
- Flat pricing across all doses with no escalation as you titrate up
- Named operating entity (Nexus Health Solutions LLC) and named physician networks (Wasef Health, Beluga Health)
The tradeoffs
- State availability is not published on the pages read this session
- A LegitScript badge was not visible in the text I could confirm today — treat that certification claim as unverified until re-checked
Regulatory note: the FDA issued a warning letter to Nexus Health Solutions LLC dba Harper Meds in June 2026. We still list and link to Harper Meds; you should know the letter is on the public record before you decide.
RxPros
68/100Where the value is
- Flat recurring price of $99.97/mo (sema) and $144.97/mo (tirz) — no per-mg price increase as you titrate up doses
- No membership fee and no mandatory commitment despite an annual-prepay discount option — 'Cancel Subscription Anytime' stated directly
- Ships a 3-month supply per order rather than monthly reshipments
The tradeoffs
- The advertised $99.97/mo (sema) and $144.97/mo (tirz) rates are NOT what a first-time buyer pays — the actual first order is $149 and $249 respectively, 49-72% higher than the headline
- Specific pharmacy partner is not named — a proprietary system routes among unnamed 503A pharmacies and 'cannot guarantee' which one fills any given order
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.