Head-to-head · Cost-Efficiency Index
Gala Health vs Amazon One Medical
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Gala Health
Women who have already committed to a full year and want one all-doses-included rate — plus, unusually, an HRT and menopause line running on the same account as the weight program.
Visit Gala HealthAmazon One Medical
Patients who specifically want a real FDA-approved branded medication (Wegovy, Zepbound, or Foundayo) rather than a compounded alternative, and already shop on Amazon.
Visit Amazon One MedicalThe verdict
Amazon One Medical takes it, leading the Cost-Efficiency Index 73 to 71. Amazon One Medical's GLP-1 program (health.amazon.com/onemedical) is a branded-only prescribing service it will not write compounded prescriptions that charges a separate ~$39 initial care fee from the medication cost itself. Gala Health still earns a C — Women who have already committed to a full year and want one all-doses-included rate — plus, unusually, an HRT and menopause line running on the same account as the weight program.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Amazon One Medical.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Gala Health | Amazon One Medical |
|---|---|---|
| Cost-Efficiency Index | 71/100 | 73/100 |
| Semaglutide / mo | No compounded option — brand Ozempic only, $1,299/mo | $299/mo (brand Wegovy, plus a separate fee) |
| Tirzepatide / mo | $179/mo (yearly subscription; $199/mo on a 3-month plan) | $299/mo (brand Zepbound) |
| Semaglutide / yr (modeled) | — | $3,588 |
| Tirzepatide / yr (modeled) | $2,148 | $3,588 |
| Coverage | 50 states claimed, no list published | All 50 states |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Yes |
| Rank here | #63 | #67 |
Gala Health
71/100Where the value is
- $179/mo on a yearly subscription, with every dose included, so the price does not climb as you titrate — dose escalation is where most flat-looking programs quietly get expensive
- The price list is PUBLIC and un-gated: the weight tier, the $149 microdosing tier and the brand tier are all printed before any quiz, intake or email capture
- Both compounded molecules — semaglutide and tirzepatide — prescribable on one account
The tradeoffs
- No month-to-month price exists anywhere on the site. "FROM $179/month" sits directly above "All doses included. Yearly subscription.", and the cheapest alternative the FAQ names is "$199 per month (with a 3-month plan)" — three months is the shortest published commitment there is
- $179/mo is $2,148 committed for the year, and that total is printed nowhere: the site quotes a monthly figure for a purchase it only sells annually, which is the single hardest cost in this ranking to compare against a rate you can cancel next month
Amazon One Medical
73/100Where the value is
- Prescribes only FDA-approved branded medications — no compounded product risk, which in this ranking only LillyDirect also avoids
- Same-day medication delivery available in roughly 3,000 cities via Amazon Pharmacy's existing logistics network
- One Medical membership is explicitly optional, not a gate, to access GLP-1 care
The tradeoffs
- The care fee (~$39-$49) and the medication cost are billed completely separately — the site itself warns 'the cost of your prescribed medication is not included with the treatment price,' so no single headline number captures the real all-in cost
- The lowest advertised Rx price ('$149 with coupon if eligible') is conditional on manufacturer coupon eligibility, not guaranteed to every patient
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.