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Head-to-head · Cost-Efficiency Index

G-Plans vs 1st Optimal

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #512

G-Plans

Shoppers wanting a nutrition/genotype-assessment angle alongside optional GLP-1 access, willing to complete a quiz to see pricing.

Visit G-Plans
VS
Grade C · #518

1st Optimal

Patients who want a named founding physician and a broader functional-medicine/hormone workup alongside GLP-1s.

Visit 1st Optimal

The verdict

Winner · G-PlansGrade C vs C

G-Plans takes it, leading the Cost-Efficiency Index 42 to 41. G-Plans is a nutrition-and-genotype-first weight-loss platform out of West Hollywood, CA that also provides access to branded and compounded GLP-1 medications (including Ozempic) after an online clinician visit. 1st Optimal still earns a CPatients who want a named founding physician and a broader functional-medicine/hormone workup alongside GLP-1s.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs G-Plans.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
45

Price Transparency

20
20

Nationwide Access

24
24

Formulation Options

53
51

Clinical Oversight

72
84

Contract Flexibility

55
37

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecG-Plans1st Optimal
Cost-Efficiency Index42/10041/100
Semaglutide / moNot disclosedNot disclosed
Tirzepatide / moNot disclosedNot disclosed
Semaglutide / yr (modeled)
Tirzepatide / yr (modeled)
CoverageCoverage not publishedCoverage not published
Oral / sublingualNoYes
Brand-name accessYesCompounded only
Rank here#512#518

G-Plans

42/100

Where the value is

  • LegitScript badge displayed
  • Confirmed access to both branded (Ozempic) and compounded GLP-1 medications
  • Distinctive nutrition-first / metabolic-genotype assessment angle vs. pure drug-dispensing competitors

The tradeoffs

  • Zero pricing visible anywhere without completing the full intake quiz
  • No named medical director or compounding pharmacy partner
Visit G-Plans

Full G-Plans review →

1st Optimal

41/100

Where the value is

  • Named founder and clinical lead: Dr. Amber Miller, a functional medicine physician
  • LegitScript verification badge displayed
  • No credit card required to start the intake quiz

The tradeoffs

  • No GLP-1 pricing published anywhere on the public site
  • No compounding pharmacy partner named
Visit 1st Optimal

Full 1st Optimal review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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