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Head-to-head · Cost-Efficiency Index

FlyteHealth vs MD Trim Clinic

Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.

Better valueGrade C · #473

FlyteHealth

Cost-first shoppers who want employers evaluating a metabolic-health benefit, not individual consumers shopping for GLP-1s directly.

Visit FlyteHealth
VS
Grade C · #478

MD Trim Clinic

Patients near Phoenix, AZ or Novato, CA who want an in-person option and don't mind discovering price only after booking.

Visit MD Trim Clinic

The verdict

Too close to callGrade C vs C

FlyteHealth and MD Trim Clinic tie on the Cost-Efficiency Index at 44/100, so neither wins outright on the numbers. For most shoppers we'd start with FlyteHealth (ranked #473, a hair above #478) — Cost-first shoppers who want employers evaluating a metabolic-health benefit, not individual consumers shopping for GLP-1s directly. But MD Trim Clinic is a genuine coin-flip alternative here.

Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs FlyteHealth.

Factor by factor

Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.

Normalized Cost/Month

45
45

Price Transparency

30
20

Nationwide Access

24
42

Formulation Options

40
40

Clinical Oversight

83
80

Contract Flexibility

55
55

Pricing, coverage & formulary

The disclosed facts behind the scores. Lower price wins its row (teal).

SpecFlyteHealthMD Trim Clinic
Cost-Efficiency Index44/10044/100
Semaglutide / moNot disclosedNot disclosed
Tirzepatide / moNot disclosedNot disclosed
Semaglutide / yr (modeled)
Tirzepatide / yr (modeled)
CoverageCoverage not published2 states
Oral / sublingualNoNo
Brand-name accessCompounded onlyCompounded only
Rank here#473#478

FlyteHealth

44/100

Where the value is

  • Backed by named enterprise broker partners (Mercer, Aon, WTW, Gallagher)
  • Publishes clinical outcome data (avg. 15% weight loss at 24 months)
  • Combines GLP-1 and non-GLP-1 treatment pathways

The tradeoffs

  • No direct-to-consumer signup or individual pricing -- access requires an employer sponsor
  • No named medical director, pharmacy partner, or LegitScript badge found
Visit FlyteHealth

Full FlyteHealth review →

MD Trim Clinic

44/100

Where the value is

  • Named medical director (Dr. Brandon Shaw, D.O.) rather than anonymous clinical leadership
  • Offers a genuine in-person option in two markets, not telehealth-only
  • Claims LegitScript-certified pharmacy sourcing (claim not independently cross-verified)

The tradeoffs

  • Zero dollar pricing published anywhere on the public site
  • Specific compounding pharmacy is not named, only described as 'a third-party pharmacy'
Visit MD Trim Clinic

Full MD Trim Clinic review →

Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.

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