Head-to-head · Cost-Efficiency Index
Curex vs Trimi Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Curex
People who want a low-cost first month, an oral option, and a verified pharmacy nationwide, and don't need a dose-by-dose price table before signing up.
Visit CurexTrimi Health
Shoppers who can pay a full year up front, where the annual rate is genuinely among the cheapest all-50 tickets — and who will otherwise budget for the month-to-month rate.
Visit Trimi HealthThe verdict
Curex takes it, leading the Cost-Efficiency Index 81 to 78. A discounted first month ($49-$149) steps up to a 'starting at $199' ongoing rate — real, but not the flat, fully-disclosed price the headline implies, and California loses the injectable route entirely. Trimi Health still earns a C — Shoppers who can pay a full year up front, where the annual rate is genuinely among the cheapest all-50 tickets — and who will otherwise budget for the month-to-month rate.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs Curex.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Curex | Trimi Health |
|---|---|---|
| Cost-Efficiency Index | 81/100 | 78/100 |
| Semaglutide / mo | $199/mo Starting (first month $49) | $175/mo month-to-month ($99/mo only on a 12-month prepay) |
| Tirzepatide / mo | $199/mo Starting (first month $149) | $235/mo month-to-month ($125/mo only on a 12-month prepay) |
| Semaglutide / yr (modeled) | $2,388 | $2,100 |
| Tirzepatide / yr (modeled) | $2,388 | $2,820 |
| Coverage | All 50 states (California: oral tablet only, no injectable) | All 50 states |
| Oral / sublingual | Yes | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #27 | #30 |
Curex
81/100Where the value is
- Discounted first month well below the ongoing rate — $49 for semaglutide, $149 for tirzepatide
- Nationwide enrollment (all 50 states) plus an oral/sublingual route as an alternative to injections
- 365-day money-back guarantee and a full refund if never prescribed
The tradeoffs
- The '$199/mo' figure is labeled 'Starting,' not flat — no dose-by-dose price table is published, so the real cost at a higher maintenance dose is unverified
- California residents cannot get the injectable route at all — oral tablets only, despite the 'all 50 states' enrollment claim
Regulatory note: the FDA issued a warning letter to Curex in September 2025. We still list and link to Curex; you should know the letter is on the public record before you decide.
Trimi Health
78/100Where the value is
- Publishes every term rung openly — annual, six-month, quarterly and monthly are all priced on the page rather than revealed at checkout
- Price is flat at every dose, so titrating up does not raise the bill
- Both molecules available on one account, nationwide, with no enrollment or consultation fee
The tradeoffs
- The advertised $99 and $125 rates require a full year paid up front; month-to-month costs $175 and $235, a 77% and 88% premium
- No public LegitScript certification, so pharmacy oversight is harder to independently verify
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.