Head-to-head · Cost-Efficiency Index
Collective vs Winona
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Collective
Shoppers who will stay on treatment for a full year, where the annual membership divides down over twelve months rather than landing on one.
Visit CollectiveWinona
Women in perimenopause or menopause who want hormone therapy online rather than GLP-1 weight-loss treatment.
Visit WinonaThe verdict
Collective takes it, leading the Cost-Efficiency Index 65 to 45. Collective sells compounded semaglutide at $59 and tirzepatide at $69 a month, both genuinely medication prices, on top of a $199 annual membership that is required, auto-renewing and not refundable. Winona still earns a C — Women in perimenopause or menopause who want hormone therapy online rather than GLP-1 weight-loss treatment.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Collective.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Collective | Winona |
|---|---|---|
| Cost-Efficiency Index | 65/100 | 45/100 |
| Semaglutide / mo | $59/moFor the medication, plus a required $199/year membership billed separately | Not disclosed |
| Tirzepatide / mo | $69/moFor the medication, plus the same required $199/year membership | Not disclosed |
| Semaglutide / yr (modeled) | $708 | — |
| Tirzepatide / yr (modeled) | $828 | — |
| Coverage | 44 states (not AL, CA, LA, MA, MS or WA) | Not published |
| Oral / sublingual | No | No |
| Brand-name access | Compounded only | Compounded only |
| Rank here | #164 | #528 |
Collective
65/100Where the value is
- Both figures are medication prices rather than a care fee with the drug billed on top, and both appear before any intake
- The membership covers unlimited doctor messaging, check-ins, dose adjustments, nutrition support and express cold shipping, all itemized
- A 21-day free trial precedes the first membership charge, and the trial's auto-conversion is stated plainly
The tradeoffs
- The headline "Get GLP-1s at $59/month" leaves out the mandatory $199 annual membership, which appears only in a card panel, a small disclaimer and the FAQ
- The membership is annual and auto-renewing, and all membership fees are non-refundable with no partial-period refund — so the cheapest medication price here cannot be bought for one month
Winona
45/100Where the value is
- Its estrogen body cream starts at $89 a month, with free shipping and unlimited follow-ups with a doctor
- Treatments are prescribed by board-certified doctors and you can pause or cancel anytime
- No blood or saliva hormone testing is required to start
The tradeoffs
- It doesn't offer semaglutide, tirzepatide or any GLP-1 weight-loss treatment
- Weight gain is treated only as a menopause symptom, with hormone therapy
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.