Head-to-head · Cost-Efficiency Index
CLYR Health vs Nirwana Health
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
CLYR Health
Shoppers comparing tirzepatide options who account for the post-first-month price increase rather than anchoring on the $149 headline.
Visit CLYR HealthNirwana Health
Cost-first shoppers who want price-sensitive shoppers willing to prepay 3-6 months to lock in the lowest advertised per-month rate.
Visit Nirwana HealthThe verdict
CLYR Health and Nirwana Health tie on the Cost-Efficiency Index at 59/100, so neither wins outright on the numbers. For most shoppers we'd start with CLYR Health (ranked #271, a hair above #275) — Shoppers comparing tirzepatide options who account for the post-first-month price increase rather than anchoring on the $149 headline. But Nirwana Health is a genuine coin-flip alternative here.
Worth knowing either way: our overall #1 pick is CoreAge Rx (Cost-Efficiency Index 94/100 — the top of the ranking). See how it stacks up: CoreAge Rx vs CLYR Health.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | CLYR Health | Nirwana Health |
|---|---|---|
| Cost-Efficiency Index | 59/100 | 59/100 |
| Semaglutide / mo | $169/mo (compounded) | $149/mo (compounded) |
| Tirzepatide / mo | $199/mo (compounded) | $279/mo (compounded) |
| Semaglutide / yr (modeled) | $2,028 | $1,788 |
| Tirzepatide / yr (modeled) | $2,388 | $3,348 |
| Coverage | Coverage not published | Coverage not published |
| Oral / sublingual | No | Yes |
| Brand-name access | Yes | Compounded only |
| Rank here | #271 | #275 |
CLYR Health
59/100Where the value is
- LegitScript Certified badge displayed
- Named prescribing medical group (MD Integrations, PC) disclosed in Terms of Service
- 503A-licensed compounding pharmacy referenced
The tradeoffs
- Tirzepatide headline price ($149) is an explicit first-month-only rate -- real ongoing cost is $199/month
- Inconsistent states-served claims ('all 50 states' vs. 'ships to 47 states') on the same site
Nirwana Health
59/100Where the value is
- Genuine LegitScript verification badge displayed
- Broad service menu (GLP-1s, hair loss, sexual wellness, anti-aging) under one account
- No insurance or membership required
The tradeoffs
- Confirmed promo-pricing trap: '$149 Introductory rate' is marketed as 'Best value' while the real no-commitment price is $199/mo
- Multi-month prepay tiers make the cheapest per-month rate only available by paying $399-plus upfront
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.